Hyaluronic Acid Powder Bulk

What is Hyaluronic Acid Powder for Skin?

Hyaluronic acid powder is a natural polymer polysaccharide consisting of disaccharide units of β1,4-D-glucuronic acid-β-1,3-N-acetylaminoglucose, which has a wide range of applications in medical aesthetics, cosmetics, and functional foods. Hyaluronic acid is classified as medical grade, medical device grade, cosmetic grade, and food grade. As a raw material, pure hyaluronic acid powder is usually used in cosmetics, medical tissue engineering, plastic surgery medical aesthetics, food field, etc.

Among them, the medical tissue engineering grade is further classified into excipient grade and injection grade according to the different levels that may be in contact with the human body. The reason why there are these levels of division is due to the hyaluronic acid powder as a raw material in different products, its application on different occasions, and the safety and performance indicators of concern are also different.

Hyaluronic Acid Powder Bulk for skin, which is applied to the surface of the skin, there is a risk that too many unspecified impurities can trigger a skin reaction for some sensitive skin. Usually, cosmetic grade hyaluronic acid powder requires a higher sodium hyaluronate content. However, skincare ingredients do not easily penetrate deep into the living cells of the skin, and impurities do not significantly affect safety and efficacy. Therefore, cosmetics grade hyaluronic acid and food grade indicators are relatively similar.

YTBIO can provide hyaluronic acid powder for skin bulk, food grade, cosmetic grade, and pharmaceutical grade hyaluronic acid powder in bulk. The production workshop is realized in a standard plant with 100,000-class cleanliness. Due to the strictly regulated production management, and scientific and rigorous process steps, to ensure the stability of pure hyaluronic acid powder between batches, the controllability of risk , and the product safety indicators can be achieved to meet the standard. At the same time, the steps of the production process are scientifically designed, statistically consistent with the scientific law, and have been extensively verified. Our cosmetic grade hyaluronic powder can provide authoritative third-party test reports.

The structure and physiological functions of hyaluronic acid

HA is composed of D-glucuronic acid and N-acetylglucosamine connected through β-1,3-glycosidic bonds to form a disaccharide unit structure, and then connected through P-1,4-glycosidic bonds to form a linear non-sulfated sugar amine. polysaccharide. At higher concentrations, its intermolecular interactions form a complex tertiary network structure.

The biological effects of HA are closely related to its mode of existence and relative molecular mass. The larger the relative molecular mass and the more complete the network structure, the better the water absorption effect. Those with more than 1000 to 5 000 repeating disaccharide unit units are high molecular weight hyaluronic acid (HMWHA), with a relative molecular mass of about 2X10^6, and those with no more than 1000 repeating units are small relative molecular mass HA ( low molecular weight hyaluronic acid (LMWHA), the relative molecular mass is less than 1 X 10^6.

What are the benefits of hyaluronic acid?

01Moisturizing

Compared with commonly used moisturizers sorbitol, propylene glycol, and sodium lactate, HA has a higher moisture absorption capacity at a lower relative humidity (30%). The longer molecular chains of HA are intertwined with each other in high-concentration solutions to form a network structure, and finally combine with water through hydrogen bonds. According to relevant surveys, the water retention value of HA can reach more than 500mL/g, and it has very significant hydrophilicity. HA is an important magic weapon for skin to always maintain elasticity and moisture. However, as age increases, the hyaluronic acid content in the skin gradually decreases, making the skin rough and elastic.

02Anti-inflammatory

In addition to moisturizing, hyaluronic acid also has a very significant anti-inflammatory effect on the skin.

Inflammation is what we usually call "inflammation". It is a self-defense response of the human body to external stimuli. It is specifically manifested as facial redness, swelling, heat, pain and dysfunction.

01HA’s inhibitory effect on inflammatory factors

Interleukins are cytokines produced by cells and transmitted to immune cells, which can activate immune cells and trigger inflammatory responses. High molecular weight HA can significantly inhibit the expression and content of interleukin, thereby reducing the adverse effects of interleukin on the skin.

02HA anti-lipid peroxidation

Lipid peroxidation is also a factor leading to skin inflammation. Lipid hydrogen peroxide, the end product of lipid peroxidation, can directly damage DNA molecules and promote the increase of malondialdehyde content in the body, leading to skin inflammation.

HA can significantly inhibit lipid peroxidation in this process, which is much higher than the inhibitory effect of VC on lipid peroxidation.

03HA reduces transepidermal water loss

As a mucopolysaccharide, HA can form a dense and breathable water-locking film on the surface of the skin, absorb moisture from the air, prevent the evaporation of water inside the skin, reduce the transepidermal water loss rate, enhance the skin barrier function, and reduce inflammation. reaction probability.

04HA scavenges reactive oxygen species

External environmental influences such as UV irradiation, air pollution, blue light radiation, etc. will cause skin keratinocytes to produce excessive amounts of reactive oxygen species ROS, which are mainly divided into superoxide radicals (O2-·) and hydroxyl radicals (·OH). Excess ROS can cause skin inflammation.

HA can resist skin damage caused by oxidation in many ways and through various action pathways. Therefore, using products containing HA will have a soothing and soothing effect on the skin. Choosing HA in conjunction with other soothing ingredients can help relieve skin sensitivity.

03 Anti-aging effect

HA is an important preventive mechanism for the formation of skin wrinkles and has significant effects in anti-aging. At the same time, HA can also remove reactive oxygen species generated by ultraviolet rays, effectively protecting the skin from excessive damage by ultraviolet rays.

As we age, the loss of hyaluronic acid in the skin gradually reduces collagen and elastic fibers in the dermis, causing skin sagging and the appearance of facial wrinkles.

04Nutritional skin

After HA acts on the skin surface, it can form a hydration film and soften the stratum corneum, thus promoting faster absorption of active substances. At the same time, HA, as an active ingredient delivery medium, creates a good external environment to make dermal collagen and elastic fibers synthesize faster and more significantly, making the nutrition supply smoother, so that the skin can maintain a better nutritional status at all times. . In addition, HA also has the function of promoting skin repair and regeneration.

What are the applications of Hyaluronic acid?

In Pharmaceutical:

Pure Hyaluronic Acid Ppowder is a biochemical drug with high clinical value, widely used in various types of ophthalmic surgery, such as crystal implantation, corneal transplantation, and anti-glaucoma surgery, etc. It can also be used for the treatment of arthritis and accelerated wound healing, at the same time, hyaluronic acid injections have also been used in medical aesthetics and cosmetic surgery, which can help to remove wrinkles and beauty and shape the role of filling.

In Cosmetics:

Hyaluronic acid is added to skin care products, toiletries, with anti-wrinkle, anti-wrinkle, beauty care and restores the physiological function of the skin, long-term use of the skin can make skin moisturized and smooth, delicate and soft, elastic.

For Health Product:

Hyaluronic acid powder for skin is mainly added to all kinds of functional food, long-term use can improve the body's moisture content, beauty, prevention and relief of osteoarthritis, osteoporosis, and other diseases, both beauty and health care functions.

Hyaluronic acid with different molecular weights has different skin care effects

The larger the molecular weight of hyaluronic acid, the stronger its ability to absorb and store water. The skin care effects of different molecular weights are different. The greater the molecular weight of hyaluronic acid, the poorer its permeability and difficulty in being absorbed by the skin, and the better its film-forming properties, making the epidermis smooth and moist. The smaller the molecular weight, the stronger the permeability, which can deeply hydrate, long-lasting moisturizing, increase skin elasticity, and improve the water storage capacity of the dermis.

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