L-5-Methyltetrahydrofolate Calcium Powder

What Is L-5-Methyltetrahydrofolate Calcium Powder?

L-5-Methyltetrahydrofolate calcium powder is a chemical substance also known as L-5-MTHF-Ca, CALCIUM L-5-METHYLTETRAHYDROFOLATE, and L-Methylfolate, calcium. This compound is the active metabolic form of folic acid and a derivative of tetrahydrofolate calcium salt. 5-Methyltetrahydrofolate is the most biologically active and functional form of folic acid. It is the only form of folic acid involved in physiological metabolism and the only form found free in animal plasma and cells. It is primarily used as an active pharmaceutical ingredient and food additive in pharmaceuticals, including preventing fetal neural tube defects and arteriosclerosis, treating megaloblastic anemia, enhancing the therapeutic effects of fluorinated pyrimidines, and treating autoimmune diseases such as psoriasis and rheumatoid arthritis.

YTBIO: Providing High-Quality L-5-Methyltetrahydrofolate Calcium Powder and Services

High-quality nutritional supplements are crucial to your health journey. YTBIO specializes in providing high-quality L-5-Methyltetrahydrofolate Calcium Powder.

Why choose YTBIO? We hold the following certifications:

- cGMP, ISO9001, and ISO22000 certifications ensure rigorous quality control throughout the entire process;

- BRC and HACCP system certifications ensure product safety and reliability;

- EU and NOP organic, kosher, and halal certifications meet various global standards and dietary requirements.

We specialize in the research, development, and production of natural plant extracts, cosmetic active ingredients, and health foods. We primarily produce plant extracts, health food ingredients, and a variety of end-use products, including capsules, softgels, granular capsules, gummies, tablets, and solid beverages. Our production facilities and equipment meet national standards, and our production processes strictly adhere to GMP requirements. If you have any questions, please feel free to contact us at sales@sxytorganic.com

Features of L-5-Methyltetrahydrofolate Calcium Powder

Stability: Highly stable, naturally present in plasma, and directly available to cells.

Absorption and Bioavailability: L-5-Methyltetrahydrofolate Calcium Powder has a bioavailability approximately two to three times that of regular folic acid, meaning it is more readily absorbed and utilized by the body.

High Bioactivity: Easily absorbed and utilized by the body compared to regular folic acid, making it more effective in boosting folate levels when supplemented with folic acid.

Biochemical Mechanism: Plays a central role in biochemical processes, participating in numerous enzymatic reactions and cofactors. It is converted in the body to S-adenosylmethionine (SAMe), which serves as a methyl group donor in various biochemical processes.

Mechanism of Action of L-5-Methyltetrahydrofolate Calcium Powder

The biochemical pathway by which folic acid exerts its biological activity involves a series of enzymatic reactions and cofactors. Absorbed folic acid is metabolized and methylated to 5-methyltetrahydrofolate (5-MTHF) in intestinal mucosal cells. This conversion is limited, and folic acid remains unchanged in the blood. S-adenosylmethionine is then converted to S-adenosylmethionine (SAMe), a methyl group donor involved in various biochemical processes. SAMe also serves as a methyl group donor in nucleotide synthesis, supporting DNA biosynthesis.

Main Benefits of L-5-Methyltetrahydrofolate Calcium powder

Promotes DNA Synthesis and Cell Growth

As the active form of folic acid, L-5-Methyltetrahydrofolate Calcium powder participates in DNA synthesis and cell growth and is essential for maintaining cellular health.

Cardiovascular Health

It helps lower homocysteine ​​levels, thereby supporting cardiovascular health.

Supports Neurological Health

Calcium L-5-methyltetrahydrofolate helps maintain a healthy nervous system and supports nervous system development.

Boosts Energy Production

It participates in energy production and hormone metabolism, which are essential for overall health.

Can Cross the Blood-Brain Barrier

It can directly cross the blood-brain barrier, which is crucial for brain health and function.

Prevents Alzheimer's Disease

It may help reduce the accumulation of beta-amyloid in the brain, thereby preventing Alzheimer's disease.

Applications of L-5-Methyltetrahydrofolate Calcium

Food Additives

Calcium L-5-methyltetrahydrofolate is widely used in the food additive field, primarily for fortifying foods to meet the folic acid nutritional needs of specific populations.

Health Supplements

In the health supplement field, it is widely used in the production of various health supplements, especially for specific populations such as pregnant women and the elderly.

Pharmaceuticals

In the pharmaceutical field, L-5-Methyltetrahydrofolate Calcium powder is primarily used to treat diseases related to folic acid deficiency and as an intermediate in drug synthesis.

Comparison of L-5-methyltetrahydrofolate calcium powder and ordinary folic acid

L-5-Methyltetrahydrofolate calcium powder and regular folic acid are both forms of folic acid, but they have some differences in bioavailability, absorption method, and applicable population.

Side Effects of Excessive Folic Acid Supplement Intake and Preventative Measures

Folic acid is an important member of the B vitamin complex, particularly important for pregnant women as it helps prevent neural tube defects in the fetus. However, excessive folic acid intake may pose some side effects and health risks.

Side Effects of Excessive Folic Acid Supplement Intake

1. Zinc Deficiency: Excessive folic acid intake may interfere with zinc metabolism, leading to low zinc levels in the body. Zinc is another essential trace mineral that is crucial for physiological functions such as the immune system, wound healing, and protein synthesis.

2. Metabolic Disorders and Neuronal Developmental Abnormalities: Studies have shown that excessive folic acid supplementation during pregnancy may increase the risk of metabolic disorders and neuronal developmental abnormalities in offspring.

3. Other Health Issues: Excessive folic acid intake may also lead to long-term health risks in offspring, such as allergic diseases, epilepsy, and autism.

Preventative Measures

1. Follow the recommended dosage: According to research, women of childbearing age should take 400-800 micrograms of folic acid daily, and women with a previous pregnancy affected by a neural tube defect should take 500 micrograms daily. Exceeding this recommended dosage may lead to the side effects listed above.

2. Regularly monitor nutritional status: By regularly checking blood levels of folate and other related nutrients, you can adjust your folate intake to avoid overdose.

3. Comprehensive nutritional supplementation: In addition to folate, you should also focus on supplementing other micronutrients, such as iron and calcium, to ensure that your overall nutritional needs are met.

4. Professional medical advice: Before starting any folic acid supplementation program, especially for individuals with specific health conditions or a family history of these conditions, consult a physician or dietitian.

YTBIO has own factory and R&D team, dedicated to providing you with high-quality L-5-methyltetrahydrofolate calcium powder and services. If you have any questions or needs, please contact us and we will respond to you as soon as possible.