L Glutathione Bulk Powder

What is glutathione powder?

L Glutathione Powdermainly exists in two forms: reduced glutathione (GSH) and oxidized glutathione (GSSG). Due to its good antioxidant and immunomodulatory effects in the body, it is widely used in food, medicine, cosmetics and other fields. As one of the essential nutrients for the human body, it has been widely used to treat diseases such as vitamin deficiency, malnutrition syndrome and low immune function caused by various reasons. It has also been proven to be of great significance in the anti-aging process. Glutathione (GSH) is a tripeptide that is produced endogenously in the human body. 

L-Glutathione Powder is found in the cells of animals and plants and is the antioxidant substance with the highest concentration in cells. For the human body, glutathione plays an extremely important role in maintaining the integrity and healthy operation of cells. An endless supply of glutathione plays an important role in intracellular antioxidant, free radical scavenging, detoxification and other functions. Indispensable element for operation.

The whitening mechanism of glutathione

L Glutathione Bulk Powder can reduce tyrosinase activity in three different ways. Tyrosinase is directly inhibited by sulfhydryl chelation of copper sites. Second, glutathione interferes with the cellular transfer of tyrosinase to promelanosomes, a prerequisite for melanin synthesis. Third, the inhibition of tyrosinase is achieved indirectly through its antioxidant effect. Glutathione transfers melanogenesis from eumelanin to pheomelanin synthesis via a reaction between sulfhydryl groups and dopaquinone, resulting in the formation of sulfhydryl-dopa conjugates. Glutathione powder has powerful antioxidant capabilities and has been shown to scavenge the production of reactive oxygen species in epidermal cells induced by ultraviolet radiation.

How powerful is glutathione?

Glutathione molecules contain γ-glutamyl and active sulfhydryl groups, which are the structural basis for many important physiological functions of glutathione.

anti-oxidation

L Glutathione is a natural reducing agent in living organisms and can be easily oxidized to GSSG, thereby protecting other substances from being oxidized. It can scavenge free radicals in the body, such as hydrogen peroxide, peroxide free radicals, etc., and protect sulfhydryl groups in proteins from being oxidized. , repair the sulfhydryl groups in the damaged protein, restore the active function of the protein, prevent cell hemolysis, promote the reduction of methemoglobin, and alleviate the discomfort caused by hypoxemia, nausea and liver disease.

Detoxify

L Glutathione has a certain detoxifying effect on the poisoning of carcinogens such as carbon monoxide, heavy metals, organic solvents, and epoxy compounds, and can be combined with them to be excreted from the body; it also protects leukopenia caused by radiation, radioactive drugs, or anti-tumor drugs. It also plays a detoxifying role in various carcinogens by helping liver metabolism, such as aflatoxin, etc.

Prevention and treatment

Bulk glutathione can be used to protect the liver and promote liver detoxification. It is often used to treat liver diseases such as alcoholism, cirrhosis, hepatitis, and fatty liver. Long-term use of glutathione can inhibit the formation of alcoholic fatty liver.

Glutathione powder is also beneficial to the maintenance of cornea and lens transparency, tissue repair and regeneration, and can also be used to treat progressive cataracts, corneal diseases and retinal diseases.

What does L Glutathione Powder do?

1. Antioxidant and anti-aging

The free radical theory believes that the aging process of organisms is the result of the accumulation of free radicals continuously produced by tissue cells of the body. The process is roughly as follows: Reactive oxygen species (ROS, reactive oxygen species) and reactive nitrogen species (RNS, reactive nitrogen species) are super active agents that act at the human cell level. Reactive oxygen species steal hydrogen atoms from the pentose sugars of DNA, causing them to form free radicals. After being oxidatively damaged, the DNA may undergo breaks, mutations, changes in thermal stability, etc., thus seriously affecting the normal transcription and translation process of genetic information. . At the same time, active oxygen will act on proteins, such as directly hydrolyzing collagen peptide chains, or causing the peptide chains to directly break from the α-carbon atom.

Reactive nitrogen reacts easily with reactive oxygen species to form peroxynitrite. Pernitrite itself is a highly reactive component that reacts directly with a variety of biological targets and components of cells, including lipids, thiols, amino acid residues, DNA bases, and low molecular weight antioxidants, Affects the structure and function of proteins, which may cause changes in enzyme catalytic activity, changes in cytoskeletal organization, and impairment of cell signal transduction.

2. GSH has a good effect in eliminating free radicals. It is the compound with the highest number and largest amount of sulfhydryl groups among the non-protein sulfhydryl compounds contained in the body. Sulfhydryl groups can scavenge a variety of free radicals, participate in cell defense mechanisms, including cell detoxification and cell damage repair, and play a key role in maintaining the stability of the body's internal environment.

3. GSH can serve as a substrate for GSH peroxidase, inhibit lipid peroxidation, protect cell membranes, and restore cell functions. Reduce free radical attacks on DNA, thereby reducing DNA damage and mutations. GSH can play a strong protective role against symptoms such as cytopenias caused by radiation, radioactive drugs, and anti-tumor drugs.

3. Whitening and improving skin

Melanin is a dark-brown pigment found in animals and plants. It is produced and stored in melanocytes. It is divided into eumelanin (dark) and pheomelanin (red). Melanocytes are probably located in the basal layer of the epidermis of the human body. When your skin is exposed to ultraviolet rays, melanocytes secrete melanin. The precursor of melanin is called tyrosine.

4. Glutathione can interfere with the synthesis of melanin. Its main mechanisms include:

Directly inhibits tyrosinase activity;

Free radicals can activate tyrosinase, and glutathione can scavenge free radicals and inhibit tyrosinase activation;

Hydrolysis to cysteine shifts the melanin synthesis pathway toward pheomelanin (rather than eumelanin, which darkens the skin).

5. Enhance immunity

The immune effects of glutathione are mainly manifested in the following three aspects:

1) Plays an important role in the immune system’s anti-infection and inflammatory response;

2) Participate in the regulation of cytokines such as leukotrienes, macrophage metastasis inhibitory factor (MIF) and IL-2;

3) Promote the proliferation of lymphocytes and monocytes. Glutathione plays an important role in the immune system's anti-infection and inflammatory response.

5. Anti-virus

Glutathione has an inhibitory effect on a variety of viruses, such as HIV, SARS-CoV, and the 2020 novel coronavirus pneumonia (COVID-19). Therefore, in the medical field, molecules that can cause an increase in glutathione levels in the body are used as immunomodulators and antibacterial and antiviral drugs.

Clinical applications of glutathione

Glutathione has a wide range of clinical effects and has a protective effect on cells. It can prevent hemolysis of red blood cells, thereby reducing the loss of methemoglobin;

Inhibits the formation of fatty liver, improves the symptoms of toxic hepatitis and infectious hepatitis; has detoxification effect on acrylonitrile, fluoride, carbon monoxide, organic solvents, heavy metals and other poisonings;

It has a relieving effect on the discomfort, nausea, vomiting, itching and other symptoms of hypoxemia and other symptoms caused by liver diseases; it maintains the balance of acetylcholine and cholinesterase, and plays an anti-allergic effect; it also has an anti-allergic effect on radiotherapy, radioactive drugs, Leukopenia caused by tumor drugs and bone marrow tissue inflammation caused by radiotherapy or drugs can play a protective role;

It can inhibit progressive cataracts and control the development of corneal and retinal diseases; it can prevent skin pigmentation and improve skin gloss; recently it was discovered that glutathione has anti-HIV effects

Glutathione applications in the food industry

Glutathione has now been widely used in various fields of food processing. In seasoned foods, when glutathione coexists with fishy substances such as sodium L-glutamate, nucleic acid, or their mixtures, it has a strong meat flavor. flavor; flavor

The use of glutathione in meat, fish and seafood foods can inhibit the decomposition of nucleic acids, enhance the flavor of food, and extend the shelf life; adding glutathione to dairy products can enhance the flavor, improve the quality of cheese, and prevent casein browning;

Adding glutathione to yogurt and baby food is equivalent to vitamin C and has a stabilizing effect; since glutathione has redox properties, adding glutathione to flour products not only has a reducing effect but also strengthens it. Amino acids; the use of glutathione can prevent pigmentation. Adding glutathione to canned fruits can prevent the browning of fruits;

Make it into different types of functional foods, such as adding it to beverages, hobbies (candy), dairy products, pasta products and fermented foods as a health care and nutritional fortifier. It can also be used for pregnant women, nursing children, and patients. Oral health products, in Japan, glutathione is considered one of the most promising health foods in the 21st century.

Glutathione (GSH) is the amazing antioxidant

Glutathione is a thiol-containing antioxidant that can scavenge free radicals that affect human health. Modern medicine believes that free radicals are one of the main causes of aging and disease. The most abundant and important antioxidant system in human cells is glutathione. Glutathione is the main force in scavenging free radicals and is hailed by scientists as the "master antioxidant" and "glutathione defense system." . Glutathione not only directly participates in scavenging free radicals, but also regulates external antioxidants such as vitamins C and E, maintaining their active (reduced) state.

Free radicals are a type of highly chemically active intermediate substances produced during the metabolism of human cells. They can attack proteins, DNA and lipid macromolecules in cell membranes, destroy the physiological functions of these biological macromolecules, and make cell membranes hard and brittle. Loss of function and shortens the life of cells; can cause gaps in the cell membrane, allowing pathogenic bacteria and viruses to invade the cells, further destroying the nuclear membrane, exposing genetic material, causing damage to genetic material, causing mutations and destruction; aggravating immune cell damage , making a damaged body with low immunity and many diseases more likely to occur.

In 1956, Professor Harman first proposed the free radical theory. He found that fishermen who worked under strong sunlight for a long time had a shorter life span. Further research proved that ultraviolet rays can stimulate the production of free radicals in the body, and free radicals can promote the aging of the physiological cycle and advance death. arrival.

Under normal conditions, pure l glutathione powder in human cells can combine with free radicals generated during human metabolism in a timely manner and convert them into low-active substances to eliminate the damage caused by free radicals to the human body.

However, as people age, the body's own ability to produce glutathione weakens, and the amount of glutathione produced is not enough to remove free radicals in the human body in a timely manner. The excess free radicals begin to destroy biological processes in cells. Macromolecule substances, cell functions are affected, and the human body begins to experience aging and disease.

In addition, some external factors: such as ultraviolet radiation, drinking, smoking, environmental pollution, certain drugs, etc., can also cause the human body to produce too many free radicals, which will increase the demand for glutathione in the human body. Once glutathione is supplied If it is insufficient, excess free radicals will damage people's health and affect their life span.

Glutathione is an irreplaceable detoxifier for:

The liver is the organ richest in glutathione in the human body, so it is also the most important organ for detoxifying xenobiotic compounds. Glutathione will bind and eliminate heavy metals entering the body; it especially binds to carcinogens to inhibit their toxicity;

Glutathione combines with toxins and is broken down outside the cells, then enters the bile or is excreted in the urine. The liver is a large warehouse for storing glutathione. People with alcoholic hepatitis and viral hepatitis (hepatitis A, hepatitis B and hepatitis C) have reduced glutathione storage. Increasing glutathione levels can restore liver function and increase glutathione. The level can better play a role in protecting the liver.

The kidney is also the organ with the richest glutathione content in the human body. Through its selective filtration function, the kidney excretes waste generated in human metabolism through urine. In addition, exogenous toxic substances, such as heavy metals, enter the human blood. , certain drugs, bacterial toxins, etc. can combine with glutathione and enter the urine through filtration and be eliminated from the body.

The kidneys play an important role in water and dielectric balance, as well as blood pressure regulation. If the kidneys do not work properly, waste and toxins accumulate in the body, which will affect other systems, especially the nervous and circulatory systems. Kidney disease can affect a person's lifespan.

In addition, human lung mucus also contains a large amount of glutathione. Studies have found that this is also closely related to the detoxification effect of glutathione. It can first react with toxic substances brought into the lungs from the air. Material combination to reduce the damage to human health caused by air pollution.

Glutathione is a vital immune booster

Neutrophils, phagocytes, lymphocytes, etc. in the human body make up the immune system in the human body. The human body has spontaneous immunity, which can resist the invasion of foreign pathogenic substances, such as bacteria, viruses, parasites, etc.; It can also solve abnormal physiological changes in the body, such as the proliferation of cancer cells, thereby maintaining the normal order of survival and protecting our health.

However, to maintain the normal operation of the immune system, immune cells must be fully activated and differentiated, and glutathione (GSH) plays a role in the full activation and differentiation of immune cells.

The human immune system is the most miraculous design of the human body to fight viruses, among which glutathione (GSH) plays an important role:

①Activate lymphocytes; ②Differentiate and proliferate T cells and B cells, and make T cells toxic to kill viruses or cancer cells.

Increasing intracellular glutathione levels is the most powerful weapon in boosting your immune system.

Glutathione is an excellent anti-aging and beauty whitening agent

The most direct manifestation of human aging is appearance. Its external manifestations are loose skin, lack of luster, and the appearance of spots, while its internal changes are caused by accelerated aging of cells, weakened regeneration ability, and deposition of pigment. .

Glutathione can effectively delay cell aging and accelerate cell regeneration. At the same time, glutathione can also affect the tyrosinase activity of skin cells, inhibit melanin production, and prevent the occurrence of skin spots.

Aging of the human body: Aging is an inevitable law in the development of human life. Under normal circumstances, people begin to age after they reach the age of thirty.

① Glutathione can increase or promote the secretion of interleukin (human growth hormone). Interleukin can regulate and slow down the shortening of telomeres and extend the life of cells, thereby extending human life.

② Glutathione is a strong antioxidant that can resist the damage of free radicals to DNA mitochondria and repair damaged DNA mitochondria; thus prolonging the cell division cycle and cell life.

③ Increase glutathione levels, neutralize and scavenge free radicals, enhance the glycolysis and oxidative phosphorylation process of sugar, and also inhibit the glycation of proteins and fats, alleviate gluconeogenesis, and stabilize proteins.

Test report on L-glutathione

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