Bulk Semaglutide

What is Semaglutide?

Bulk Semaglutide is a second-generation GLP-1 analog developed by diabetes giant Novo Nordisk, consisting of 31 amino acids. Compared with natural GLP-1, it has undergone several structural modifications, including the replacement of alanine at position 8 with monoaminoisobutyric acid, which increases resistance to dipeptidyl peptidase-4 (DPP-4); the addition of octadecane diacid to lysine at position 26, which enhances the binding ability to albumin, prolongs the plasma half-life and reduces renal clearance; lysine at position 34 is replaced by arginine, which enhances the stability of the drug. It can promote insulin secretion and inhibit glucagon secretion. Because semaglutide can reduce hunger, reduce diet, and reduce calorie intake, it is considered to be useful for the treatment of obesity.

Semaglutide Weight Loss Mechanism

It is an analog of GLP-1 and has 94% homology with the human GLP-1 sequence. As a GLP-1 receptor agonist, it binds to the GLP-1 receptor and initiates a series of events that reduce blood sugar, including stimulating insulin secretion and reducing glucagon secretion.

Weight loss

It reduces food intake by inhibiting the absorption of glucose in the intestine, thereby achieving the effect of weight loss.

Improving blood sugar control

It can increase the body's sensitivity to insulin, accelerate the entry of glucose into cells for metabolism, and help control hyperglycemia.

Reducing appetite

It can stimulate satiety signals in the central nervous system and reduce the desire to eat, thereby reducing appetite.

Improving blood lipid levels

It can effectively reduce the concentration of low-density lipoprotein cholesterol, thereby improving blood lipid levels and preventing the occurrence of cardiovascular diseases.

Promoting the recovery of pancreatic cell function

It can increase the number and activity of pancreatic β cells, enhance their ability to secrete insulin, and help restore damaged pancreatic cell function.

What Are The Functions?

Antioxidant

It can remove free radicals in the body, reduce the damage caused by oxidation, and protect cells from damage.

Hypoglycemic

It can effectively lower blood sugar levels by enhancing insulin secretion and inhibiting glucagon secretion, and is suitable for the treatment of type 2 diabetes.

Weight loss treatment

Semaglutide Powder can act on the digestive tract, delay gastrointestinal emptying, increase satiety, and inhibit appetite and reduce food intake by acting on the brain, thereby helping to lose weight.

Immunomodulatory

It can enhance the activity of immune cells, especially macrophages and lymphocytes, and improve the body's immunity.

Promote growth and development

It can stimulate cell growth and differentiation, which helps to increase weight and improve physical fitness.

Lipid-lowering

It can reduce the content of cholesterol and triglycerides in the blood, which helps to prevent and treat related diseases such as hyperlipidemia.

Production Process

1.Chemical method

It is a medium-long peptide containing 31 amino acid residues. If the standard chemical method is used, the process steps are many and the cycle is long. The resin shrinks severely during the step-by-step coupling, resulting in incomplete reaction and easy production of defective peptides, resulting in many impurities in the product and great difficulty in purification. If the solid-phase fragment condensation method is used, each fragment needs to be in large excess, there are many side reactions, and the product separation is difficult. In short, the chemical method has low yield, high cost, and requires a large amount of organic solvents, which is not suitable for industrial production.

2.Biological method

The typical method of the biological method is to obtain the main peptide chain of semaglutide by yeast production through genetic recombination technology, and then connect the remaining short peptides after the main peptide chain is modified by the side chain. This method has short steps and the product purification is simple and easy compared to the chemical method. Compared with chemical synthesis, the production capacity of the biosynthesis process is not limited, there is no residual solvent, and the purity is high.

Application

Medical and Health

Semaglutide Powder is used to treat diabetes and obesity, improve patients' health and reduce the risk of related complications.

Nutrition and Weight Management

It can be used as a weight loss drug for weight management and obesity treatment to help patients control their weight.

Certificates

YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Bulk Semaglutide and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.

Packaging and Shipping

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