Bulk Ivy Leaf Extract

How much do you know about Bulk Ivy Leaf Extract?

Ivy is native to Europe, Asia, and North Africa, and is primarily distributed in southwest, southeast, and northwest China. Ivy prefers partial shade and partial sun, and can be grown in corners and crevices. It grows epiphytically on tree trunks or on damp rock faces in broadleaf forests. Ivy can be harvested year-round, typically in autumn, cut into sections, and sun-dried. The entire plant is used medicinally, as are its fruits (hedera seeds). Cosmetics primarily use its dried stems and leaves.
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Bulk Ivy Leaf Extract is extracted from its leaves. Its primary use is to promote respiratory health, but it can also be used on the skin to combat aging.

​​​What are the main ingredients of Bulk Ivy Leaf Extract?

The main ingredients include triterpenoid saponins, collectively known as hederacosides, as well as inositol, carotene, sugars, and tannins. Hederacoside C, hederagenine, and hederacoside D are the main components of the extract. Common specifications include: 5%-20% hederagenine total glycosides, 5%-10% hederagenine C.

Hederacoside C & D

What are the main benefits of Bulk Ivy Leaf Extract?

The main benefits of ivy extract include relieving respiratory symptoms, providing anti-inflammatory and antioxidant benefits, assisting with skin care, and inhibiting microbial activity. Its mechanism of action is related to its saponins and flavonoids, and it is commonly used to improve respiratory health and local inflammation.

For the Respiratory System

1. Antitussive and Expectorant

The saponins in ivy extract relax bronchial smooth muscle, promote sputum discharge, and relieve cough symptoms. It is often used as an adjunctive treatment for acute and chronic bronchitis and asthma. Studies have shown that it can reduce inflammation in the respiratory mucosa and improve airway obstruction.

2. Relieve Nasal Congestion

By constricting nasal mucosal blood vessels and reducing secretions, it is often used to relieve nasal congestion caused by allergic rhinitis or colds.

About Anti-Inflammation and Antioxidant Properties

Inhibit Inflammatory Responses

Flavonoids can block the release of inflammatory mediators (such as prostaglandins), reducing symptoms such as redness, swelling, and pain, and have a certain effect on relieving inflammation of the skin or mucous membranes. 2. Free Radical Scavenging

Antioxidant ingredients can reduce oxidative stress damage, slow cell aging, and help prevent chronic diseases.

For Skin

1. Promotes Wound Healing

Topical application can accelerate epidermal repair and reduce scarring. It is suitable for minor burns, abrasions, or eczema.

2. Relieves Skin Inflammation

Antibacterial and anti-inflammatory properties can help improve inflammatory skin conditions such as acne and dermatitis.

Antibacterial

Experiments have shown that this extract has a certain inhibitory effect on pathogens such as Staphylococcus aureus.

What are the main applications of Bulk Ivy Leaf Extract?

Medicine

It is commonly used for respiratory conditions such as asthma and bronchitis. It can improve lung function and reduce coughing and wheezing. Studies have shown that this extract has significant effects on both childhood bronchitis and adult COPD.

Cosmetics

It is widely used in skincare products to promote collagen synthesis, increase skin hydration, and reduce wrinkles and age spots. Its antioxidant properties protect the skin from UV damage and increase skin elasticity, making it a valuable ingredient in anti-aging skincare products.

Health Supplements

In health supplements, ivy extract is primarily used for respiratory and digestive health, as well as immune health. Its antioxidant, anti-inflammatory, and anti-allergic properties help maintain overall health.

Is Bulk Ivy Leaf Extract used in Personal Care?

Ivy extract can inhibit the activity of apolipoproteins, which play an important physiological role in lipoprotein metabolism. Excessive activity in sweat glands can easily produce odor, leading to underarm odor. Therefore, ivy extract's ability to inhibit apolipoprotein activity can help reduce underarm odor. Furthermore, ivy extract has an inhibitory effect on Corynebacterium xerosis, a bacterium that produces androstenone in the human body and contributes to odor. Therefore, ivy extract can be used in odor-control products. Because it inhibits cortical secretions, it is also suitable for oily skin.

Products containing ivy extract also have wrinkle-reducing properties. It can help reduce fine lines on the face. Furthermore, ointments can relieve pain associated with osteoarthritis and rheumatism, help strengthen bones, and reduce joint inflammation. When the skin is inflamed, burned, or injured, ivy extract can promote cell regeneration and healing.

​​​​​​​Sweat Glands

​​​​​​​Biological Activity of Hederagenin

Comparative studies of the biological activities of soapberry saponins and hederagenin reveal relevant biological properties of hederagenin.

Comparative Antioxidant Activity

Studies have shown that both hederagenin and soapberry saponins exhibit antioxidant effects, but hederagenin exhibits greater activity. Experiments have found that even relatively low doses of hederagenin significantly increase the activity of antioxidant enzymes (such as superoxide dismutase) and reduce the levels of oxidative damage markers (such as malondialdehyde). In contrast, soapberry saponins require higher doses to achieve similar antioxidant effects, and their activation of certain antioxidant enzymes is still inferior to that of hederagenin. Therefore, hederagenin exhibits superior antioxidant properties.

Comparative Anti-Inflammatory Activity

Both soapberry saponins and hederagenin exhibit anti-inflammatory effects, but hederagenin exhibits a stronger anti-inflammatory effect. Experiments have found that hederagenin significantly inhibits inflammatory responses at relatively low doses, while soapberry saponins require higher doses to achieve similar effects. Furthermore, soapberry saponins may exert their anti-inflammatory effects by modulating certain inflammatory signaling pathways and have demonstrated protective potential in hypertensive rats in animal studies.

Comparative Antidepressant Activity

Studies have shown that an ethanol extract of the fruit of the Chinese genus Hederagenin exhibits antidepressant effects, with hederagenin being its primary active ingredient. Experiments have shown that hederagenin can improve depressive symptoms by regulating the dopamine and serotonin neurotransmitter systems, with superior efficacy compared to the ethanol extract. In cell-based experiments, hederagenin also demonstrated protective effects on neurons, suggesting its potential to repair depression-related neural damage.

Comparison of Hypoglycemic Effects

Hederagenin exhibits multiple mechanisms for lowering blood sugar: inhibiting key glucose metabolism enzymes such as α-glucosidase and amylase, reducing glucose production; promoting insulin secretion, lowering glucagon, and increasing liver and muscle glycogen stores; and regulating protein tyrosine phosphatase 1B (PTP1B), improving insulin resistance. Experimental studies have shown that its blood sugar-lowering effects are even superior to those of some synthetic drugs. In contrast, studies on the blood sugar-lowering effects of soapberry saponins are limited, and existing studies are mostly based on crude extracts, making it unclear whether the active ingredients are saponins. Therefore, hederagenin's mechanism of action is more clearly defined and offers greater potential for lowering blood sugar.​​​​​​​

Comparison of Lipid-Lowering Effects

Compared to the side effects of traditional lipid-lowering drugs, plant saponins have attracted attention due to their natural and low-toxic properties. Studies have shown that hederagenin can effectively reduce triglyceride levels and protect liver cell function without cytotoxicity. Furthermore, soapberry saponins, while lowering blood lipids, can also protect the vascular endothelium and prevent thrombosis. Experimental data show that soapberry saponins are more effective in clearing triglycerides, but hedera hederagenin still has potential application value in regulating blood lipid metabolism.

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Summary

These findings indicate that hederagenin possesses remarkable biological activity, including outstanding anti-inflammatory, antidepressant, and antioxidant activities. Hederagenin exhibits significant hypoglycemic effects through multiple mechanisms. These findings suggest that hederagenin is a natural active ingredient with significant development potential, particularly in the areas of anti-inflammatory, neuroprotective, and blood sugar regulation.

YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Bulk Ivy Leaf Extract Powder and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.