Detection method: HPLC
Source: Cyanotis arachnoidea extract
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What is ecdysone?
Cyanotis arachnoidea C. B. Clarke, also known as pearl dewweed, cockscomb ginseng, anemarrhena, etc., is a perennial procumbent herbaceous plant of the genus Dewweed in the family Commelinaceae. Spider-silk blue-eared grass is distributed in southern China, Taiwan, and Southeast Asia.
The whole plant of Cyanotis arachnoidea mainly contains phytosterone compounds, including 26 phytosterone components. β-ecdysterone, α-ecdysterone, turkesterone, and podosterone, among which β-ecdysterone has the highest content.
Ecdysone powder is a kind of substance with strong molting activity, which can promote cell growth. It can stimulate the division of dermal cells and produce new epidermis to cause insects to molt. It can promote protein synthesis in the human body.
This type of compound was first discovered in insects, but the existence of ecdysone was first reported in the plant kingdom in 1966. The roots and leaves of many ferns and higher plants contain this type of compound. For example, hydroxyecdysterone and achysterone were found in the roots of Achyranthes bidentata grown in Taiwan, and achyrososterone was isolated from the roots of Achyranthes bidentata.
The main structural feature of ecdysone is that the steroid core has a 7-position double bond and a 6-keto group, as well as multiple hydroxyl groups, so it has greater solubility in water.
The activity of this type of hormone is related to the cis form of the A/B ring, that is, 5β-, because 5α-epiecdysterone has no metamorphic hormone activity. Ecdysone not only promotes protein synthesis, but also has biological activities such as eliminating cholesterol from the body, lowering blood lipids, and inhibiting the rise in blood sugar.
Ecdysone acts on the human body to promote protein synthesis, remove cholesterol from the body, lower blood lipids, inhibit the rise of blood sugar and other physiological activities. It is used among the people for rheumatoid arthritis. In sericulture, it is used to shorten the age of silkworms and promote silk spinning and cocooning; in aquaculture, it is also widely used in the breeding of shrimps and crabs; in cosmetics, ecdysone is also used as a special additive; molting Hormones are added to cosmetics to prevent dry skin and make the skin more delicate. Ecdysone can affect all developmental stages of insects from hatched larvae to adults, so it controls or kills agricultural pests. It has been developed and applied as a third-generation pesticide; ecdysone also has certain effects on the physiological processes of crops. , it also has good development and application prospects in crop yield auxiliaries.
What are the benefits?
1. Health product effects: lower blood lipids, lower blood sugar
Hydroxyecdysone can inhibit hepatic glucose synthesis, so it has a hypoglycemic function independent of insulin. Can induce phosphorylation of protein kinase (AKT) in hepatocytes.
2. Health product efficacy: Promote protein synthesis
Ecdysterone synthesizes protein by increasing amino acids. This process is fast, effective, and can last for a long time. Its ability to stimulate muscle cells to synthesize protein is very significant.
3. Health product effects: anti-fatigue, lower cholesterol
Stabilizes the state of damaged cells affected by cortisol (high levels of cortisol can lead to increased blood sugar, increased appetite, weight gain, decreased libido and extreme fatigue), normalizes the process of energy synthesis (ATP and creatine), and Improves liver function so the body can quickly adapt to changes in environment and stress. There is no interaction with hormones during this process.
By promoting the conversion of cholesterol to bile acids, ecdysterone shows potential as a cholesterol-lowering agent. Studies have found that its cholesterol-lowering effect is 2.5mg per kilogram of body weight.
4. Cosmetic effects: Promote cell division and growth in the dermal layer, repair skin
What is used is high-purity ecdysterone (β-ecdysterone content is greater than 90% under HPLC high-performance liquid phase detection), which is a pure white crystalline powder. It has a single ingredient, no other impurities, no allergic reaction to the skin, has strong permeability, can be quickly absorbed by the skin in a liquid state, and enhances cell metabolism and activity.
It has good exfoliation, freckle removal and whitening effects, and has a good repair effect on facial chloasma, traumatic dark spots, freckles, melanin pigmentation, etc. It also has obvious effects on acne. The functional principle of ecdysterone is to act on the skin itself, causing cells to divide and grow, increasing collagen, removing freckles, whitening, and repairing skin texture from a deep perspective. Therefore, it is different from other products that supplement collagen from the outside and can achieve fundamental improvement. Effect on skin condition.
5. Agricultural breeding effects:
In aquatic products, ecdysone can cause shrimps and crabs to shed their shells in time, remove harmful parasites from the body, thereby accelerating growth; promote metabolism and protein synthesis in the body, enhance anti-stress; significantly improve the consistency of shrimp and crab shelling, and effectively avoid each other Mass killing greatly improves the survival rate; the product contains bactericidal and antibacterial ingredients, which can effectively improve the ability of shrimps and crabs to resist diseases.
In sericulture, ecdysone can shorten the age of silkworms, make the clusters neater, and promote silk spinning and cocooning.
In terms of pesticides, ecdysone can affect all developmental stages of insects from hatched larvae to adults, so it controls or kills agricultural pests. It is now being developed and applied as a third-generation pesticide; the effect of ecdysone on the physiological processes of crops It also has certain effects and has good development and application prospects in crop yield auxiliaries.
6. Pharmacological effects
Hydroxyecdysone acts on the human body by promoting collagen synthesis, anti-arrhythmia, and anti-fatigue; promoting cell growth, stimulating dermal cell division, and removing cholesterol from the body; lowering blood lipids, inhibiting blood sugar rise; stimulating menstruation, dehumidification, and analgesia, etc. Active; it is a natural anti-cancer preparation; since the advent of dewgrass ecdysone in 1976, irregular tablets, injections, and ointments have been developed.
Health care products application
In terms of sports health products, ecdysone has a significant ability to stimulate protein synthesis in the muscle cytoplasm by increasing the assembly of amino acids into protein chains, and this ability goes back to the translation and migration process of protein growth. Ecdysone is not only beneficial to health but also safe. It helps stabilize cells during cortisol damage, normalizes energy synthesis steps (ATP and sarcosine) and improves liver function so that the organism can quickly adapt to environmental and stress changes. .
Bulk Ecdysone powder is used in sericulture to shorten the age of silkworms, tidy up the clusters, and promote spinning and cocooning; ecdysone is necessary for the growth and development, shelling and metamorphosis of aquatic crustaceans - shrimps and crabs. Substance is the main raw material of "shelling hormone"; this product is suitable for the artificial breeding of shrimps, crabs and other aquatic crustaceans and ground worms. After adding this product, the shrimps and crabs can shell smoothly and promote the shelling of shrimps and crabs. The consistency of the shells effectively prevents individuals from killing each other and significantly improves the breeding survival rate and product specifications.
In cosmetics, specially treated high-purity ecdysone, also called "ecdysterone", is generally used. It is a pure white crystalline powder or colorless transparent crystal. It has a single ingredient, no allergic reaction to the skin, and has very good properties. It has strong permeability and can be quickly absorbed by the skin in liquid state; it is an effective substance that can enhance cell metabolism and activation, and has good exfoliation, spot removal and whitening effects. It can treat facial chloasma, traumatic dark spots, freckles, It has a very good repair effect on melanin pigmentation, etc., and it also has a significant effect on acne. It is far superior to any product currently on the market in promoting collagen synthesis.
Ecdysone has a good effect on fading chloasma, pigmentation, traumatic dark spots, and freckles on the face, and has a significant effect on acne; it can make the skin lesions of the elderly flatten and blemishes disappear, and simple pityriasis disappear, facial wrinkles become shallower, and normal skin becomes more beautiful. Moisturizing and lustrous ecdysone is a promising plant-derived skin care cosmetic additive. It is an effective substance that can enhance cell metabolism and activation, and has good exfoliation, spot removal and whitening effects. It has a very good repair effect on facial chloasma, traumatic dark spots, freckles, melanin pigmentation, etc. It also has obvious effects on acne. High-purity ecdysone refined by a special process is used in cosmetics. The product specifications are HPLC 98% (high performance liquid chromatography), and the dosage is: 0.1~0.35%. In the cosmetics industry, it can be used in facial creams, essences, lotions, etc.
In general, ecdysone HPLC ≥ 60% (mostly 90, 95) is used for human health care, making tablets, capsules, etc., with the effect of increasing muscle protein, athlete health care, etc.; ecdysone HPLC ≥ 50%, aquaculture; molting Hormone HPLC ≥98% crystal powder, widely used in cosmetics.
More than 50 studies have shown that ecdysone has no side effects, no hormonal interactions, and extremely low levels of toxicity.
In 1998, ICN biochemical experiments tested it, and the data showed that in order for ecdysone to show toxicity, it must reach an ultra-high dose of 6400mg/kg. Furthermore, no effects of ecdysone on the mammalian hormonal system have been reported in endocrine tests of growth hormone and luteinizing hormone.
The widely accepted dose is 5 mg/kg per day. For people who suffer from stress and fatigue due to a fast pace of life, the recommended dose of ecdysone is 300-400mg per day. Higher doses such as 400-600mg per day are more suitable for exercise.
Yuantai Organic Bio is committed to providing customers with the highest-quality bulk Ecdysterone Powder and services so that every consumer can enjoy natural, healthy, and high-quality food. If you have any inquiries or needs about our products, please feel free to contact us, and we will reply to you as soon as possible.
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