Glucoraphanin

Broccoli Seed Extract Glucoraphanin Powder Supplier/1%-20% Available

YTBIO's broccoli Glucoraphanin powder is derived from pure natural raw materials: broccoli seeds from broccoli farms. Specifications include 1%–20% Glucoraphanin. The entire production process, from raw materials to finished product, is controllable and traceable.Glucoraphanin powder is a natural active ingredient primarily found in broccoli seeds and seedlings. It is one of the most effective Nrf2 activators currently available, activating various cell-protective functions such as detoxification, anti-oxidation, and anti-inflammation.

Why Choose YTBIO？

YTBIO offers various specifications of Glucoraphanin ranging from 1% to 20%. Please contact us for detailed product information.

We possess mature plant extraction technology and strictly control the content of active ingredients to ensure product purity.

Each batch of our products undergoes HPLC content testing and multiple quality tests, including microbial and heavy metal testing.

YTBIO has 12 years of experience in the plant extract industry, owns its own factory, collaborates with multiple domestic planting bases, and has passed international certifications such as cGMP, ISO9001, ISO22000, FSSC22000, BRC, Kosher, and Halal.

From plant raw material supply to finished product customization, YTBIO provides complete OEM/ODM services.

Please contact us for more product specifications and information

What are the Benefits of Glucoraphanin?

Antioxidant activity

Mariati et al. Broccoli extract was inoculated into a mixed fermenter with Lactobacillus bulgaricus, Streptococcus thermophilus, Lactobacillus acidophilus and Bifidobacteria bifidum, and 20% of the fermentor inoculum was fermented for 24 hours to determine the antioxidant activity of fermented broccoli. Reaching the maximum, the total phenolic content decreased at this time, indicating that the material basis of the antioxidant capacity of the fermentation products may not be polyphenols, but related to active substances such as glucoraphanin in broccoli extract.

Regulation of intestinal flora

Thioglycosides and glucoraphanin-rich broccoli extract have been shown to modulate gut microbiota. An exploratory study shows that consumption of glucoraphanin-rich sauerkraut results in changes in the composition of the gut microbiota in subjects, with a significant increase in the abundance of lactic acid bacteria associated with sauerkraut fermentation, such as Lactobacillus plantarum and Lactobacillus brevis. . In a placebo-controlled, semi-open-label intervention by Yanaka et al., patients with chronic functional constipation consumed 20 g of glucoraphanin-rich broccoli sprouts or glucoraphanin-free alfalfa sprouts daily for 4 weeks. Compared with alfalfa sprout consumption, broccoli sprout consumption significantly reduced Constipation Scoring System scores, increased bowel movement frequency, shortened bowel movement time, and increased the proportion of butyric acid-producing Bifidobacteria. and Clostridium XVIa in the intestinal flora.

Relieve metabolic syndrome

In recent years, broccoli extract glucoraphanin and its active metabolites have shown good properties in reducing fat accumulation, improving insulin sensitivity, and reducing inflammation. Its potential to alleviate metabolic syndrome has attracted the attention of researchers. Xu Xingxing et al. added broccoli freeze-dried powder or glucoraphanin powder to the feed and fed mice on a high-fat diet for 8 weeks. They found that feeding glucoraphanin effectively inhibited body weight, liver mass, mesenteric fat, kidney The increase in lipid accumulation in peripheral fat not only reduces the level of oxidative stress in the liver, but also upregulates lipid levels related to lipid accumulation, inhibits the increase in body weight and liver mass, and reduces the accumulation of epididymal fat, mesenteric fat, and perirenal fat. , reduce the level of oxidative stress and upregulate peroxisome proliferator-activated receptor α (PPARα), carnitine palmitoyltransferase-1 (CPT1) and peroxisomal acyl-coenzyme related to lipid metabolism in the liver A-oxidase (ACOX) gene expression, whereas feeding broccoli had no effect on the dietary effects of a high-fat diet on body weight and liver mass and on lipid accumulation in ependymal, mesenteric, and perirenal fat. Broccoli improved lipid metabolism less in mice fed a high-fat diet than in mice fed glucoraphanin powder.

Fight stomach inflammation and improve digestive system

Although few microorganisms can survive in the highly acidic and hypoxic environment of our stomach, Helicobacter pylori is a special case. It can cause chronic inflammation of our stomach and even lead to ulcers, and studies have shown that this bacterium is associated with gastric cancer and various lymphoid tissue cancers. Now, researchers have found that it can directly act on this bacteria, thereby protecting the gastrointestinal mucosa of patients and reducing inflammation.

Strengthen brain vitality and resist neurological diseases

Scientists from various countries have been conducting research on brain nerves for a long time. Nowadays, sulforaphane has also been studied to have beneficial effects on the brain, and these studies have been further extended to several common neurological diseases, such as Alzheimer's disease (AD), Parkinson's disease, Huntington's disease, and amyotrophic lateral disease. Sclerosis, multiple sclerosis, autism spectrum disorder, and schizophrenia. And some preclinical studies have shown that glucoraphanin has multi-faceted neuroprotective effects on AD pathophysiology.

What are the Applications?

In the food industry:

Glucoraphanin is used in nutritional supplements and functional foods to develop products with antioxidant properties.

In the pharmaceutical industry:

It can also be used as an intermediate in the pharmaceutical field.

In the daily chemical industry:

Due to its antioxidant and anti-inflammatory properties, it can be added to skincare products, offering certain whitening and anti-aging effects.

Outlook

Glucooraphanin is a natural product with potent biological activity, exhibiting excellent pharmacological efficacy in areas such as anticancer, anti-inflammatory, and antioxidant activity, attracting widespread attention. 

However, two points warrant further attention. First, while glucoraphanin possesses high safety, producing no significant toxicity even at doses exceeding a hundred times the normal usage level, its rapid metabolism and excretion limit its clinical application. Second, glucoraphanin exhibits poor stability, necessitating careful consideration of appropriate dosage forms during drug development.

This can typically be improved by using cyclodextrin or starch to create inclusion complexes, or by using sulforaphane as a lead compound for structural modification, thereby enhancing both efficacy and stability.

Contact Us

YTBIO supplies high-quality Glucoraphanin (content 1%–20%) extracted from broccoli. Contact us now for product specifications, samples, and customized quotes.

Tel:86-029-86478251 / 86-029-86119593

Whatsapp:8617782577059

Email:sales@sxytorganic.com

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