Glucoraphanin Powder

Product Name:Broccoli Seed Extract Glucoraphanin Powder
Latin Name:Brassica oleracea L.var.italic Planch.
CAS No.:21414-41-5
Source:Broccoli Seed
Active Ingredients:glucoraphanin
Testing Method:HPLC
Appearance:Light Yellow Powder
Pesticide Residue:Comply with (EC) No 396/2005 Standard
Storage conditions: This product should be sealed and shaded, stored in a dry
Shipping speed:1-3 days

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Product Introduction

What is Broccoli Seed Extract Glucoraphanin Powder?

Glucoraphanin Powder is a natural active product mainly present in broccoli seeds and seedlings, which can be converted into sulforaphane through the action of black mustard enzymes or intestinal microorganisms. Glucoraphanin is currently one of the strongest activators of Nrf2, which can activate various cellular protective effects such as detoxification, antioxidant, and anti-inflammatory. Glucoraphanin belongs to a naturally occurring "thioglucoside" compound in cruciferous vegetables.

YTBIO supplies Broccoli Glucoraphanin Powder from purely natural sources, the raw material broccoli seeds from broccoli planting bases, the Glucoraphanin Powder content is high, up to 20%. The products from raw materials to finished products, the production of the whole process of controllable and traceable, and a variety of pollutants are detected in line with global standards.


What are the benefits of Glucoraphanin Powder?

Antioxidant activity

Mariati et al. Broccoli extract was inoculated into a mixed fermenter with Lactobacillus bulgaricus, Streptococcus thermophilus, Lactobacillus acidophilus and Bifidobacteria bifidum, and 20% of the fermentor inoculum was fermented for 24 hours to determine the antioxidant activity of fermented broccoli. Reaching the maximum, the total phenolic content decreased at this time, indicating that the material basis of the antioxidant capacity of the fermentation products may not be polyphenols, but related to active substances such as glucoraphanin in broccoli extract.

Regulation of intestinal flora

Thioglycosides and glucoraphanin-rich broccoli extract have been shown to modulate gut microbiota. An exploratory study shows that consumption of glucoraphanin-rich sauerkraut results in changes in the composition of the gut microbiota in subjects, with a significant increase in the abundance of lactic acid bacteria associated with sauerkraut fermentation, such as Lactobacillus plantarum and Lactobacillus brevis. . In a placebo-controlled, semi-open-label intervention by Yanaka et al., patients with chronic functional constipation consumed 20 g of glucoraphanin-rich broccoli sprouts or glucoraphanin-free alfalfa sprouts daily for 4 weeks. Compared with alfalfa sprout consumption, broccoli sprout consumption significantly reduced Constipation Scoring System scores, increased bowel movement frequency, shortened bowel movement time, and increased the proportion of butyric acid-producing Bifidobacteria. and Clostridium XVIa in the intestinal flora.

Relieve metabolic syndrome

In recent years, broccoli extract glucoraphanin and its active metabolites have shown good properties in reducing fat accumulation, improving insulin sensitivity, and reducing inflammation. Its potential to alleviate metabolic syndrome has attracted the attention of researchers. Xu Xingxing et al. added broccoli freeze-dried powder or glucoraphanin powder to the feed and fed mice on a high-fat diet for 8 weeks. They found that feeding glucoraphanin effectively inhibited body weight, liver mass, mesenteric fat, kidney The increase in lipid accumulation in peripheral fat not only reduces the level of oxidative stress in the liver, but also upregulates lipid levels related to lipid accumulation, inhibits the increase in body weight and liver mass, and reduces the accumulation of epididymal fat, mesenteric fat, and perirenal fat. , reduce the level of oxidative stress and upregulate peroxisome proliferator-activated receptor α (PPARα), carnitine palmitoyltransferase-1 (CPT1) and peroxisomal acyl-coenzyme related to lipid metabolism in the liver A-oxidase (ACOX) gene expression, whereas feeding broccoli had no effect on the dietary effects of a high-fat diet on body weight and liver mass and on lipid accumulation in ependymal, mesenteric, and perirenal fat. Broccoli improved lipid metabolism less in mice fed a high-fat diet than in mice fed glucoraphanin powder.

Fight stomach inflammation and improve digestive system

Although few microorganisms can survive in the highly acidic and hypoxic environment of our stomach, Helicobacter pylori is a special case. It can cause chronic inflammation of our stomach and even lead to ulcers, and studies have shown that this bacterium is associated with gastric cancer and various lymphoid tissue cancers. Now, researchers have found that it can directly act on this bacteria, thereby protecting the gastrointestinal mucosa of patients and reducing inflammation.

Strengthen brain vitality and resist neurological diseases

Scientists from various countries have been conducting research on brain nerves for a long time. Nowadays, sulforaphane has also been studied to have beneficial effects on the brain, and these studies have been further extended to several common neurological diseases, such as Alzheimer's disease (AD), Parkinson's disease, Huntington's disease, and amyotrophic lateral disease. Sclerosis, multiple sclerosis, autism spectrum disorder, and schizophrenia. And some preclinical studies have shown that glucoraphanin has multi-faceted neuroprotective effects on AD pathophysiology.

What are the applications of Glucoraphanin powder?

In the Food Field:

In 2001, researchers for the first time used glucoraphanin in nutritional supplements and functional foods, and this functional food became popular in Europe and the US. In 2016, broccoli seed extract passed the GRAS (Generally Recognised As Safe) certification of the Food and Drug Administration of the U.S.; and in 2017, aqueous extracts of broccoli seeds, containing 13-20% glucoraphanin, were approved as a new food ingredient in China. It officially included broccoli seed aqueous extract in the food ingredient database. This means that glucoraphanin can be widely used in the food industry from now on.

In Pharmaceutical:

Glucoraphanin powder is also used in the pharmaceutical field as an intermediate.



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