Pure Quercetin Powder

Product Name:Quercetin
Main Specification:95%
Source:Sophora Japonica Bud
Apperance: greenish Yellow or Yellow Fine Powder
CAS No.:6151-25-3
Chemical Formula: C15H14O9
Molecular Weight:338.27
Package Method:25/Drum or according to client‵s requirement
Storage conditions: This product should be sealed and shaded, stored in a dry
Certifications:ISO9001,ISO22000,Kosher,Halal,HACCP
Shipping speed:1-3 days

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Product Introduction

What is quercetin powder?

Quercetin is a bioflavonoid that is widely found in vegetables and fruits and has a variety of biological activities. Pure Quercetin Powder can strengthen the body's enzyme antioxidant system, has antioxidant and free radical scavenging effects, and also has anti-oxidant properties. inflammatory, antiviral and immunomodulatory effects. Quercetin has strong antioxidant capacity and has a good preventive effect on diseases caused by oxidative stress.

Quercetin Bulk Powder is a yellow crystal or powder solid with a hydroxyl group in the molecule. Its chemical structural formula is shown in the figure and it has a stable molecular structure. Quercetin molecules are almost insoluble in water, but slightly soluble in cold and hot ethanol, and completely soluble in dimethyl sulfoxide. In addition, quercetin also has good stability and antioxidant properties and is widely used in medicine, food and other fields.

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Extraction process of quercetin

1. Natural extraction and isolation

Since the content of quercetin in plants is only a few thousandths to a few thousandths, and its extraction and separation is difficult and costly, extracting quercetin directly from plants is not practical in production. However, when analyzing and identifying flavonoids or preparing analytically pure samples, quercetin extraction and separation technology must be used.

 

2. Acid hydrolysis method

The rutin (rutin) of quercetin is widely distributed in nature and has high content. For example, the content in sophora rice is as high as more than 20%. Rutin is first extracted from Sophora japonica and then acid hydrolyzed to produce quercetin. This method is feasible for production.

 

The main extraction methods of rutin include alkali extraction and acid precipitation, organic solvent extraction, and dipping. Among them, the alkali extraction and acid precipitation method is the most practical. Choose a 0.05% NaOH solution and boil it for 20 minutes, filter it while it is hot, and extract it 4 times with the same method to obtain an alkali aqueous solution of rutin. Add acid to precipitate it. After filtering, add acid to hydrolyze it to obtain water-insoluble quercetin. Filter , washed with water and dried to obtain quercetin solid. 

 

3. Enzyme conversion method

Enzymatic hydrolysis of rutin is used to prepare a large amount of quercetin monomer, which is less abundant in plants. The operation is simple and safe. The whole process is economical and practical. The output is large and suitable for industrial production. The purity of the product is >90%, which can meet the needs of food and clinical applications. Therefore, enzymatic conversion is undoubtedly a promising preparation method.

Benefits of Quercetin Powder

1. Antioxidant

Pure Quercetin Powder is a powerful antioxidant in nature, its antioxidant capacity is 50 times that of vitamin E and 20 times that of vitamin C. Studies have shown that quercetin has good scavenging effects on superoxide anions, hydroxyl radicals and singlet oxygen, and there is an obvious dose-effect relationship.

2. Anti-inflammatory effect

Quercetin can inhibit the production and gene expression of TNF-α and the expression of inflammatory mediator genes by regulating NF-κB, thereby reducing the release of inflammatory mediators. Quercetin’s antioxidant effects also help reduce inflammation.

In a 1-month randomized, double-blind controlled crossover trial, the research subjects were 30 patients with chronic pelvic pain. The experimental group took 500mg of quercetin daily, and the control group took a placebo daily. The study showed that the experimental group The patient's symptoms improved significantly.

3. Protect cardiovascular system

The cardiovascular protective effects of quercetin are mainly reflected in five aspects:

① Dilate blood vessels and lower blood pressure: For example, quercetin can inhibit the release of endothelin, reduce blood vessel tone, and thereby lower blood pressure.

② Prevent and treat coronary heart disease: Through animal experiments, the function of reducing the incidence and mortality of myocardial infarction and lowering blood sugar has also been discovered;

③ Reduce cardiac hypertrophy; Quercetin can significantly inhibit the increase in total protein content of cardiomyocytes caused by angiotensin II, significantly increase SOD activity, reduce MDA content, and have a significant preventive and therapeutic effect on cardiomyocyte hypertrophy.

④Inhibit the proliferation and hypertrophy of vascular smooth muscle cells;

⑤Anti-thrombosis.

4. Quercetin and respiratory diseases

Quercetin Bulk Powder has good expectorant and cough-relieving effects, and has a certain antiasthmatic effect. It has been used to treat chronic bronchitis for a long time. Quercetin's effects on respiratory health are achieved through mucus secretion, anti-viral, anti-fibrosis, anti-inflammatory and other pathways.

Quercetin also has a wide range of anti-fibrotic effects, including anti-fibrosis of the liver, lungs, heart and kidneys. Its mechanism of action is relatively complex, including inhibiting fibroblast proliferation, inhibiting collagen synthesis, preventing oxidative damage, inhibiting angiogenesis, etc. .

5. Antibacterial effect

Quercetin has broad-spectrum antibacterial properties and is more effective against Gram-negative bacteria than Gram-positive bacteria.

6. Skin color enhancement and skin protection effects

In addition, quercetin can also interfere with collagen transcription, and combined with radiation, significantly reduces collagen synthesis in keloid fibroblasts cultured in vitro. Therefore, quercetin has the potential to become a new keloid treatment.

7. Other functions

Quercetin has a variety of biological activities. In addition to the above values, it also has hypoglycemic, antidiarrheal, antiviral, antithrombotic, analgesic, anti-obesity, antidepressant, liver protection and other effects.

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What Is The Difference Between Quercetin, Quercetin Dihydrate And Quercetin Anhydrous?

①Concept:

Quercetin on the market generally refers to quercetin dihydrate, quercetin dihydrate is because the molecular structure contains

two crystal waters; and anhydrous quercetin is two crystal waters in the molecular structure Removed, that is, the product of

hydrogenation of the double bonds at the 2 and 3 positions in the quercetin core.

②Solubility:

Quercetin dihydrate and quercetin of anhydrous are almost insoluble in water, but dihydroquercetin after hydrogenation of

the double bond of quercetin is soluble in water.

③Plant source:

Anhydrous quercetin is obtained by dihydroquercetin becoming anhydrous at 95-97 degrees Celsius and removing two crystal waters.

There are two kinds of sources, one is obtained by hydrogenating the double bond at the 2 and 3 positions in the core of quercetin,

and the other is obtained from larch tree segments.

④Properties:

Quercetin dihydrate, quercetin of anhydrous, and dihydroquercetin are all yellow powder, and dihydroquercetin is slightly

brighter and lighter in color.

 

Certificates

YTBIO is committed to providing customers with the highest-quality Pure Quercetin Powder bulk and services so that every consumer can enjoy natural, healthy, and high-quality food. If you have any inquiries or needs about our products, please feel free to contact us, and we will reply to you as soon as possible.

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