Do You Know The Effect Of Codonopsis Pilosula Extarct Powder?

Codonopsis pilosula, medicinal material character, middle and lower part sometimes branched, 15-40cm long, 0.6cm-5cm in diameter. The surface is gray or grayish brown, with longitudinal sulcus and sparse and transverse long dermal pores, 5-10cm on the upper end, and some of the rings are fine, and the root head has wart-like stem marks, commonly known as "lion pan head", and the broken place is often black brown gelatinous. The quality is slightly hard, the section skin part yellowish white, many cracks, wood part yellowish. The air is slightly fragrant and the taste is bitter.

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Pharmacological effects of Codonopsis Pilosula Extarct Powder

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1. Enhance the function of reticuloendothelial system

Codonopsis ginseng can significantly enhance the function of reticuloendothelial system, especially when combined with Astragalus membranaceus and ganoderma lucidum.Because it can enhance the phagocytic function of reticuloendothelial system, it can improve the disease resistance of the body, which is consistent with the treatment of Qi deficiency, so that the body can achieve the role of centralization.

2. Blood tonic effect

When Codonopsis codonopsis was given orally or subcutaneously, the red blood cells of rabbits were increased. In addition, Codonopsis codonopsis was injected into the stomach of mice, the red blood cells were increased and hemoglobin was significantly increased.Subcutaneous injection can increase the white blood cell reticulocyte significantly and also has therapeutic effect on leukocytosis caused by chemotherapy drugs such as cyclophosphamide and radiotherapy.

3. Effects on adrenal cortical function

Codonopsis pilosula decoction can increase the amount of plasma corticosterone no matter it is intravenously injected or intraperitoneally injected into mice. Its active components are saponins and saccharides, which can partially antagonize the decrease of plasma corticosterone caused by dexamethasone, acting on the level above the pituitary gland.

4. Resistance to fatigue

Codonopsis codonopsis extract was given to mice by gavage, and then its effect on swimming was observed. The results showed that it could significantly improve their swimming ability and slow down the development of fatigue. The mechanism may be related to improving the excitability of the central nervous system and improving the activity ability of the body, so it could reduce their fatigue sense.

5. Effects and effects on cyclic adenosine

The concentration of cAMP in plasma and spleen decreased slightly by intraperitoneal injection of Codonopsis pilosula decoction into mice. A small increase in cAMP can enhance the body's immune function.

6. High temperature resistance

Mice were subcutaneously injected with 0.2ml of 100% codonopsis codonopsis aqueous solution and then placed in 45-47℃ oven. The results showed that the survival time of the drug group was significantly longer than that of the control group, indicating that the temperature resistance ability of mice could be significantly improved, which may be due to codonopsis codonopsis has the strong effect of ginseng and the anti-shock effect.

7. Effects on the cardiovascular system

Codonophenine has obvious antihypertensive effect, and its extract can increase cardiac output without increasing heart rate, and can increase blood volume in brain, lower limbs and viscera. It is also reported that the extract of Codonopsis pilosula has obvious antihypertensive effect on epinephrine.

8. Regulation of the intestinal tract

Codonopsis saponin can regulate the intestinal tract and resist the effects of acetylcholine, 5-hydroxytryptamine, histamine and barium ammoniate on the intestinal tract in different degrees. Therefore, the effect of codonopsis ginseng on spleen and stomach is certain in clinic.

9. Promote coagulation

Codonopsis injection can promote coagulation and proved to be free of hemolysis.

10. Blood glucose raising effect

Each mouse was given 0.5g of dangshen injection, and the rabbit was given 1g intravenously (or 6g/kg of decoction by gavage). The results showed that it had the effect of increasing blood glucose. In addition, the mouse experiment also showed that the injection had an antiglycemic effect on insulin induced hypoglycemia. Its effect of raising blood glucose may be related to its high sugar content.

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