What Effect Does Ginkgo Leaf Have?

Ginkgo biloba is a plant with high medicinal value. Ginkgo biloba, also known as ginkgo or Gongsun tree, belongs to the gymnosperms, and all other plants of its family have become extinct and are called "relict plants". Ginkgo biloba, deciduous trees, up to 40 meters high, branches have long branches short branches, young tree bark light gray brown, shallow longitudinal crack, old gray brown, deep longitudinal crack. Leaves are spirally scattered on long branches and in 3-5 clusters on short branches; Stalks 3-10 cm long; Leaf scalloped, pale green, glabrous, with many 2-forked parallel veinlets, upper margin 5-8 cm wide, shallowly undulate, sometimes lobed or deeply lobed centrally. Dioecious. Flowers unisexual, sparsely homologous. Convolvulus born in axils of scaly leaves at the tip of short branches, male convolvulus catkin shape, pendulous; Female convolvulus has long peduncle, peduncle end is often divided into 2 forks, each fork has a disc shaped nucellus, each plant has an ovule, only one develops into seeds. Seeds drupe, elliptic to subglobose; Outer coat fleshy, whitish, yellowish or orange-yellow when ripe; Middle seed coat bony, white; Endosperm coat membranous, endosperm rich. Flowering from March to April, seed maturity from September to October. 

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Ginkgo leaf extract powder is a kind of powder extracted from ginkgo leaf. What are its efficacy and function? Follow me below to find out.

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The main effective components of ginkgo biloba leaf extract are flavonoids and ginkgolides. The extract has functions of promoting blood circulation, removing stasis and clearing collaterals, etc. It is used in many drugs for cardiovascular and cerebrovascular diseases. It has magical effect on treating coronary heart disease, angina pectoris, hepatic arteriosclerosis, senile dementia, hypertension and other diseases.

Pharmacological action of ginkgo leaf extract

(1) All parts of ginkgo fruit, especially glycolic acid, can inhibit the growth of tuberculosis bacilli and inhibit various bacteria and skin fungi to varying degrees in vitro. Overeating ginkgo can cause poisoning, abdominal pain, vomiting and diarrhea, fever, cyanosis and coma, convulsions, severe respiratory paralysis death.

(2) Ginkgo biloba leaf extract has different degree of inhibition on a variety of Gram-negative and positive bacteria and skin fungi. It has the function of expectorant and weak relaxation of bronchial smooth muscle. Have anti-aging effect, ginkgo armour has anti-allergic effect.

Clinical effect of Ginkgo Leaf Extract

1. Treat hypertension

Due to elevated blood pressure and inadequate perfusion of blood vessels in hypertensive patients, tissue ischemia produces a large number of superoxide anion free radicals, resulting in lipid peroxidation damage and increased MDA content. This pathological process is closely related to the occurrence of hypertension. In the process of ginkgo biloba extract in the treatment of high blood pressure, can be directly capture and remove etc on superoxide anion free radicals and hydrogen peroxide, prevent and inhibit free radicals and lipid peroxidation reaction pathological, inhibition of lipid peroxide (LPO) and its metabolite such as MDA and conjugated diene side material generated, blood pressure returned to normal.

2. Treatment of hyperlipemia

Ginkgo biloba extract has a therapeutic effect on hyperlipidemia, can significantly reduce the level of blood lipid, reduce the incidence of coronary heart disease in the elderly. WitteS et al. found that taking ginkgo biloba extract 761240mg/d for 12 weeks can significantly improve fibrinogen and blood characteristics in patients with coronary heart disease, hypertension, hyperlipidemia and diabetes, and treatment can reduce the long-term effects of cardiovascular risk factors.

3. Treatment of pulmonary heart disease

The platelet aggregation function (PAG) of patients with pulmonary heart disease increased at all times, the slope increased, and the depolymerization rate decreased, while the erythrocyte secondary increased, the compliance decreased, the blood viscosity increased, and the blood was in a state of hypercoagulation. The increase of PAF is an important reason for the increase of PAG. The blood PAF in patients with pulmonary heart disease and bronchial asthma is significantly increased. The inhibitory effect of ginkgo biloba extract on PAF decreased platelet aggregation, blood viscosity, pulmonary arteriole thrombosis and PAG. At the same time, it can antagonize the contractile response of lung tissue to histamine and PAF and improve lung function, so it plays an important role in the treatment of pulmonary heart disease.

4. Treat coronary heart disease angina pectoris

Ginkgo biloba extract has obvious effect on the treatment of coronary heart disease angina pectoris, has the function of improving heart blood flow, protecting ischemic myocardium, can reduce cholesterol, triglyceride, increase high-density lipoprotein, significantly improve the clinical symptoms of coronary heart disease patients, has important significance for the prevention of cardiovascular and cerebrovascular diseases.

5. Treatment of cerebrovascular diseases

Through the clinical application of ginkgo biloba extract preparation, it is found that it can improve cell blood circulation and activate cell metabolism, so it has a significant effect on senile dementia, sequela of brain injury, cerebral thrombosis and other diseases. Another study reported that patients with Alzheimer's disease, multiple cerebral infarction vascular dementia, and mixed dementia, graded by geriatric examination, took ginkgo biloba extract for 6 months. The incidence of dependency and care need, concentration of memory and attention, and clinical general impression grading showed significant improvement. EGh has been approved by the German federal Government's Health department as a treatment for alzheimer's disease.

A study in the United States also confirmed that Ginkgo biloba is effective in treating Alzheimer's disease and multiple cerebral infarction dementia, with no obvious adverse effects. The extraction of ginkgo biloba leaves in the treatment of patients with mental disorder after cerebral infarction has significant effects on increasing cerebral blood flow and improving microcirculation, but also can inhibit the reduction of glucuronic acid transferase caused by hypoxia, improve the energy metabolism of hypoxia brain cells, and improve the hypoxia metabolism of brain cells. Ninety-two patients were compared before and after treatment with scale method. After 3 months, cognitive function was improved, especially attention, short-term memory and learning ability, and some patients reached normal standard.

6. Treatment of eye vascular diseases

Glaucoma is a chronic progressive optic neuropathy in which the chronic progressive loss of retinal ganglion cells is the main pathophysiological feature. Optic neuroprotection is appropriate for diseases in which cells are slowly lost. Optic neuroprotective drugs should have the following conditions: ① animal experiments have confirmed the optic neuroprotective effect of the drug, ② molecular biology has confirmed its mechanism of action, ③ the drug z~10 reach the target cells, ④ The multi-center clinical control experiment has confirmed. Ginkgo biloba leaf extraction has all the above conditions and is applied to the treatment of glaucoma. Ginkgo biloba extract has obvious effect on diabetic retinopathy and proliferative retinopathy.

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