Oryzanol 99%

Do You Know What Is Oryzanol 99%?

Oryzanol 99% is a fat-soluble vitamin found in high concentrations in rice bran, especially in germinated brown rice, hence the name "rice bran."Oryzanol 99% is a natural organic compound found widely in cereal seeds. It is a mixture of ferulate esters, primarily composed of campesterol ferulate, cycloartenol ferulate, and 24-methylenecycloartenol ferulate.

Because oryzanol 99% is derived from a natural product and is not only non-toxic but also beneficial to human health, it has garnered widespread attention and has gained favor in clinical medicine. Numerous clinical studies have shown that oryzanol has the following benefits: protecting the skin, lowering blood sugar, inhibiting cholesterol synthesis and reducing serum cholesterol levels, regulating autonomic nerves, and improving gastrointestinal function.

Oral oryzanol is poorly soluble in water. The intestinal absorption rate of oral oryzanol is only approximately 5%, compared to 40% for animal cholesterol. Due to their structural similarities, oryzanol competitively inhibits cholesterol absorption in the intestine, significantly increasing fecal cholesterol levels. The portion absorbed into the bloodstream inhibits the formation of low-density lipoprotein (LDL) in the liver.

YTBIO: Providing You With High-quality Oryzanol 99% And Services

Common Production Methods of Oryzanol 99%

Extraction methods include adsorption and weak acid substitution.

The weak acid substitution process involves two major steps: alkali refining and capture, and weak acid precipitation and separation. The oryzanol content in crude bran oil is 2%-3%. First, oryzanol (which has phenolic properties) is mixed with NaOH to produce a sodium salt. This greatly increases the hydrophilicity of the sodium oryzanol salt, making it easily adsorbed and precipitated by alkaline soap. Two alkali refining steps in the crude bran oil concentrate 80%-90% of the oryzanol in the secondary soapstock, achieving capture. The soapstock is then further saponified to improve its physical properties, allowing for oryzanol separation. Alkaline methanol, which dissolves the sodium oryzanol salt and fatty acid soaps while not dissolving unsaponifiables such as bran wax, fatty alcohols, and sterols, allows the sodium oryzanol salt to be separated from the viscous unsaponifiables. A weak organic acid 99% is then used to decompose the sodium oryzanol salt and reduce the oryzanol to obtain the product.

What Are The Effects Of Oryzanol 99%?

Oryzanol and Vitamins

Although its name is similar to vitamins, oryzanol is not a vitamin. Oryzanol 99% is a fat-soluble compound found in high concentrations in rice bran, especially in germinated brown rice, hence the name "rice bran." Oyzanol is a natural organic compound found widely in cereal seeds.

The human body's sympathetic nervous system is divided into sympathetic and parasympathetic nerves, which mutually regulate and balance each other, controlling organ activity and glandular secretions.

Autonomic nervous system dysfunction can cause abnormalities in multiple systems, including the nervous system, circulation, and digestive system. Therefore, oryzanol can be used to regulate illnesses caused by autonomic nervous system dysfunction.

Improving Sleep Quality

Older adults often experience insomnia, which may be related to autonomic nervous system dysfunction. oryzanol can regulate the autonomic nervous system, reduce endocrine imbalances, and thus improve symptoms of mental and neurological disorders.

Oryzanol is very effective for mild to moderate insomnia, especially in middle-aged and elderly individuals.

Antioxidant and Anti-Aging Effects

Older adults experience decreased metabolic activity and weakened antioxidant capacity, leading to increased oxidative stress and accelerated aging. Oryzanol effectively scavenges free radicals and reduces lipid peroxidation.

Research has shown that oryzanol can enhance the activity of superoxide dismutase and glutathione peroxidase, inhibiting oxidative stress and protecting cell membranes and mitochondrial function. After 12 weeks of continuous oryzanol consumption in elderly individuals, serum levels of oxidative stress markers significantly decreased and antioxidant enzyme activity increased.

Oryzanol 99% also has anti-inflammatory properties. Chronic inflammation is common in the elderly, and taking oryzanol can reduce inflammatory markers and alleviate joint pain and stiffness.

Cognitive Function Protection

Oryzanol 99%, with its excellent antioxidant and anti-inflammatory properties, provides a strong defense for neurons against oxidative stress and inflammation.

Research has shown that oryzanol can effectively inhibit the accumulation of beta-amyloid protein, reduce oxidative damage, and alleviate neuroinflammation, thereby protecting the function of hippocampal neurons. A study of elderly patients with mild cognitive impairment (MCI) revealed that those taking oryzanol achieved significant improvements in cognitive performance (MMSE scores), with an average increase of 3 points, while the placebo group showed no significant change.

Relieves Menopausal Symptoms

Menopausal syndrome is a common group of symptoms experienced by elderly women around the time of menopause, including palpitations, restlessness, insomnia, depression, excessive sweating, irritability, and mood swings. Oryzanol, a commonly used medication for treating menopausal syndrome, can improve these symptoms by regulating autonomic nervous system function.

Assists in Regulating Blood Lipids

With aging, the elderly are more likely to develop dyslipidemia. Oryzanol has multiple physiological functions, including lowering blood lipids, reducing liver lipids, preventing lipid oxidation, and acting as an antioxidant. It can increase cholesterol excretion in bile and feces, reduce cholesterol absorption, and thus improve blood lipid levels. This is important for preventing arteriosclerosis and cardiovascular disease.

Relieves Migraines

Migraines are a common headache type in the elderly, often accompanied by symptoms such as anxiety, tension, and emotional instability. Oyzanol has a strong sedative effect and can improve neurological symptoms in migraine sufferers.

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Gastrointestinal Health

With aging, elderly people may experience a gradual decline in gastrointestinal function, making them more susceptible to chronic enteritis, the discomfort associated with enteritis, and symptoms such as abdominal pain and diarrhea caused by autonomic nervous system disorders. The sterols in oryzanol have antibacterial and anti-inflammatory properties and can alleviate these symptoms. Oyzanol 99% also regulates autonomic nervous system function, improves gastrointestinal motility, and promotes digestion.

Applications of Oryzanol 99%

Oysterol is primarily used in medicine and nutritional supplements:

Medically

It is used to treat neurological disorders such as neurasthenia and neurosis, and to relieve symptoms such as anxiety, tension, and insomnia.

It is used as an adjunct to the treatment of menopausal syndrome and premenstrual syndrome, alleviating symptoms such as hot flashes, mood swings, and breast tenderness.

It is used to improve psychiatric symptoms caused by autonomic dysfunction, such as mood swings and anxiety.​​​​​​​

Nutritional Supplements

As a natural nutrient, oryzanol can be consumed through whole grain foods rich in oryzanol, such as brown rice and whole wheat, helping to maintain good health and prevent nutritional deficiencies.

Some Medication Combinations For Oryzanol Tablets

Oryzanol Tablets + Vitamin B1 tablets

oryzanol primarily acts on the autonomic nervous system and endocrine centers of the diencephalon, regulating autonomic nervous system function, reducing endocrine imbalance, and improving symptoms of neuropsychiatric disorders. Autonomic dysfunction is caused by a variety of factors, such as chronic mental stress and excessive psychological pressure, which can lead to an imbalance between the sympathetic and parasympathetic nervous systems. Vitamin B1 is a key component of coenzymes required for glucose metabolism, maintaining normal glucose metabolism and the function of the nervous and digestive systems. Combining these two can improve symptoms of autonomic dysfunction, such as insomnia, anxiety, and excessive sweating, by regulating nerve function and maintaining normal neural metabolism.

Oryzanol tablets + doxepin tablets

oryzanol can regulate autonomic nervous system function and, to a certain extent, alleviate anxiety-related physical symptoms, such as palpitations and hot flashes. Anxiety disorder is a psychiatric disorder characterized by anxiety, associated with neurotransmitter imbalances and autonomic dysfunction. Doxepin is a tricyclic antidepressant with antidepressant and anxiolytic effects, primarily exerting its effects by inhibiting the reuptake of norepinephrine and serotonin by nerve endings. The combination of oryzanol and doxepin can synergistically improve anxiety symptoms. Oryzanol regulates autonomic nervous system function to help alleviate the physical symptoms of anxiety, while doxepin alleviates anxiety through its neurotransmitter effect.

Oryzanol + Melatonin

Oryzanol can regulate autonomic nervous system function, reduce cerebral cortical excitability, and play a role in promoting sleep. Insomnia has many causes, including psychological and physiological factors, with autonomic dysfunction being a key factor. Melatonin is an amine hormone secreted by the pineal gland in the brain, primarily regulating the sleep-wake cycle. The combination of oryzanol and melatonin, with oryzanol modulating nervous system function and melatonin regulating the circadian rhythm, can jointly improve insomnia and enhance sleep quality.

Oryzanol Tablets + Flupentixol-Melitracen tablets

Oryzanol regulates autonomic nervous system function and improves symptoms of autonomic dysfunction such as hot flashes and palpitations caused by hormonal changes during menopause. Menopausal syndrome is caused by ovarian dysfunction and decreased estrogen levels in women, leading to neuroendocrine dysfunction. Flupentixol-Melitracen is a combination antidepressant and antianxiety medication that regulates central nervous system function and improves mood and physical symptoms. Combined use can synergistically improve various symptoms of menopausal women, such as mood swings, insomnia, and excessive sweating, helping to alleviate menopausal syndrome.

Oryzanol Tablets + Compound Lactobacillus Acidophilus tablets

Oryzanol regulates the autonomic nervous system. Autonomic nervous system dysfunction can affect gastrointestinal digestion. Functional dyspepsia is primarily caused by gastrointestinal motility disorders and sensory abnormalities. Compound Lactobacillus Acidophilus can regulate the balance of intestinal flora, improve the intestinal microecological environment, and promote digestion. When used in combination, oryzanol stabilizes the autonomic nervous system, and compound Lactobacillus acidophilus improves intestinal flora, promoting gastrointestinal function recovery from different angles and relieving the symptoms of functional dyspepsia.

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