Pure Chitosan Powder

What is chitosan?

Pure Chitosan Powder is obtained by deacetylation of chitin, which is widely found in nature. Its chemical name is polyglucosamine (1-4)-2-amino-B-D glucose. It was first obtained by Frenchman Rouget in 1859. After chitosan, this natural polymer has attracted widespread attention from all walks of life for its excellent properties such as biofunctionality, compatibility, blood compatibility, safety, and microbial degradability. It is widely used in medicine, food, chemical industry, cosmetics, water, etc. Significant progress has been made in applied research in many fields such as processing, metal extraction and recovery, biochemical and biomedical engineering. For patients, there have been research reports on the effects of chitosan on lowering blood lipids and blood sugar.

The chemical name of chitosan is (1,4)-2-amino-2-deoxy-β-D-glucan, also known as chitosan. Chitosan is the N-deacetylation product of chitin, which is the second most abundant natural polymer substance in nature after cellulose. It is widely present in lower arthropods, crustaceans (such as shrimps, Crabs, crustacean insects) and the cell walls of lower plants (such as algae, fungi). Therefore, chitosan has a wide range of sources and is abundant in nature. It is also the only natural alkaline cationic polymer known so far. It has the characteristics of good biodegradability, good biocompatibility, low cytotoxicity and large reserves. , often called the sixth life element of the human body. According to statistics, chitosan can be widely used in fields such as medicine, food industry, daily chemicals, agriculture, biotechnology and sewage treatment.

The structure of chitosan

Chitosan is the N-deacetylation product of chitin (β-(1,4)-2-acetamido-2-deoxy-D-glucan). The chitosan molecule has a linear structure, which is similar to the molecular structure of plant cellulose. The only difference is that the hydroxyl group on the C2 position of cellulose is replaced by an amino group. However, the chemical properties are quite different, and the intramolecular hydrogen bonds are stronger. The structure is tightly arranged and easy to crystallize, resulting in poor solubility in most solvents. Chitosan also has a complex double helix structure. The amino and hydroxyl groups in the linking units have high reactivity and can be chemically modified to introduce other groups, thereby giving chitosan good solubility in different solvents. sex and functionality.

What are the benefits?

1.Analgesic effect

Chitosan dressing has a very good soothing effect on wound pain. Domestic and foreign experts have found that chitosan can have a cooling and comfortable emollient effect when it comes into contact with wounds. Recently, Okamoto et al. studied the analgesic effect mechanism of chitosan on inflammatory pain induced by dilute acetic acid solution and found that chitosan has an analgesic effect by absorbing protons released by acetic acid at the inflammatory site.

2. Coagulation

Bulk Chitosan has a hemostatic effect and can promote coagulation and thrombus formation. Blood coagulation experiments conducted by scientists have shown that chitosan has the effect of accelerating hemostasis and coagulating red blood cells in the blood of humans and animals. It is believed that this is due to the positive charge carried by the chitosan molecular chain and the negative charge on the cell surface. The mutual attraction of charged muramic acids produces adhesion. The adhesion between chitosan and red blood cells causes cell aggregation, thereby promoting blood coagulation and stopping bleeding.

3. Antibacterial effect

Scientific researchers have found that chitosan and its derivatives have a very good inhibitory effect on bacteria, yeast, fungi and other microorganisms, and are effective against bacteria found on the human epidermis, such as Staphylococcus epidermidis, Escherichia coli and Candida albicans tropicalis. Pseudomonas aeruginosa, Staphylococcus aureus and suppurative Staphylococcus aureus infections that are prone to occur in burn patients have significant inhibitory effects. One view is that the interaction between the positive charge in the chitosan molecule and the negative charge in the microbial cell membrane leads to the leakage of bacterial proteins and other cell components, resulting in an antibacterial effect. When the pH value is small, the C-2 position on the chitosan molecular chain carries more positive charges than chitin, and its antibacterial properties are better than chitin. In addition, chitosan can stimulate the resistance of many tissues; acts as a water-based bonding agent and inhibits different enzymes; low molecular weight chitosan can enter the cells of microorganisms and inhibit cell growth by inhibiting the conversion of DNA into RNA.

4. Anti-inflammatory effect

In general, materials with positively charged surfaces can easily cause severe inflammatory reactions when used as medical materials due to their strong irreversible bacterial adhesion. Although the primary amino group in the chitosan molecule can easily produce a -NH3+ structure in acidic media, it does not usually cause inflammation. It can be seen from the Zeta potential on the surface of chitosan with different degrees of deacetylation that due to the weak alkalinity of chitosan, the Zeta potential on its surface is not a very high positive value, which indicates that the chitosan dressing will not affect the surrounding tissue. Produces a strong stimulating effect and has anti-inflammatory effects.

5.Physiological effects and efficacy

Chitosan is a dietary fiber that has the effects of lowering serum cholesterol, regulating intestinal flora, and lowering blood pressure. After the human body ingests chitosan, fecal analysis shows that it is hardly digested and absorbed, so it is a type of dietary fiber.

Studies have shown that chitosan has some of the properties of dietary fiber, such as water retention, swelling, adsorption and indigestion and absorption. It can promote peristalsis of the digestive tract, adsorb toxic substances, increase defecation volume, and reduce abdominal and intestinal pressure. , improve the occurrence of constipation, etc.

Chitosan has similar physical and chemical effects to gastric mucin. It has the functions of inhibiting gastric acid, anti-gastric ulcer, and anti-inflammatory. It is a polysaccharide that resists gastric acid. When exposed to water, it swells into a viscous pulp and has adhesive force. A protective membrane can be formed in the stomach to reduce gastric acid irritation to the ulcer surface.

Food safety: When animals are fed chitosan at a dosage of 20% of the feed, animal death has been reported. According to analysis, this is because high concentrations of chitosan form gels in the internal organs of animals, inhibiting the animals' absorption of nutrients. At present, it is necessary to systematically study the physiological effects of high-viscosity macromolecules and low-viscosity small molecules of chitosan, and further long-term chronic tests on the safety, toxicology and metabolism of chitosan from clear sources are needed.

Application direction

Thickeners, stabilizers, gelling agents, binders. It is also used to prevent mildew in acidic substances and can form a transparent semi-permeable film on the surface. Used for pickled products, baked products, bread, oily foods, etc.

Mainly used in food, medicine, agricultural seeds, daily chemicals, industrial wastewater treatment and other industries. Chitosan oligosaccharide has the functions of improving immunity, activating cells, lowering blood lipids, lowering blood pressure, anti-aging, regulating the body environment, etc., and can be used in the fields of medicine, health care, and food. In the field of environmental protection, chitosan can be used in sewage treatment, protein recovery, water purification, etc. In the field of functional materials, chitosan can be used in membrane materials, carriers, adsorbents, fibers, medical materials, etc. In the field of light textiles, chitosan can be used in fabric finishing, health underwear, papermaking auxiliaries, etc. In the agricultural field, it can be used in feed addition, seed treatment, soil improvement, fruit preservation, etc. In the field of tobacco, chitosan is a tobacco sheet glue with good performance, and has the characteristics of improving taste, non-toxic and odorless when burning.

Pure Chitosan Powder is a biocompatible, antibacterial and biodegradable polyelectrolyte with a wide range of biomedical and industrial applications. Its chemical properties and low toxicity allow it to be used as a component of drugs, in gene transfer systems, as biodegradable membranes, and as a scaffold in tissue engineering.

Bulk Chitosan supplier

Yuantai Organic Bio is committed to providing customers with the highest-quality Pure Chitosan Powder and services so that every consumer can enjoy natural, healthy, and high-quality food. If you have any inquiries or needs about our products, please feel free to contact us, and we will reply to you as soon as possible.

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