Vitamin K2 Bulk

Vitamin K2 Bulk

CAS:27670-94-6,863-61-6
Specifications: K2-MK7, K2-MK4
Shelf Life: 24 Months
Inventory: In Stock
Certificates:cGMP,ISO22000,ISO9001,EU&NOP Organic Certificate,Kosher,BRC,Halal,HACCP
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Product Introduction

Are You Familiar With Vitamin K2 Bulk?

Vitamin K2 bulk is a natural, fat-soluble vitamin available in various forms, including MK-4, MK-6, and MK-7. MK-4 and MK-7 are the most common forms in supplements, with MK-7 having a longer half-life and being more convenient for daily supplementation, leading to its wider use.

Vitamin K2's primary function is to promote calcium absorption. It effectively activates several key calcium-regulating proteins in the body, precisely regulating calcium's distribution, ensuring that calcium is deposited in bones and away from soft tissues such as blood vessels. This enhances bone calcification while lowering blood calcium concentrations. It works by activating osteocalcin (OC) and matrix gamma-carboxyglutamate protein (MGP).

Vitamin K2 is known for its positive effects on bone health, cardiovascular health, and overall well-being. As more people prioritize maintaining good health and preventing chronic diseases, vitamin K2 is gaining increasing attention. Vitamin K2 is used in a variety of applications, including dietary supplements and infant formulas, and is available in a variety of dosage forms, including powders, capsules, and drops.

Vitamin K2 Bulk

Main Sources of Vitamin K2 Bulk

Vitamin K2 Bulk's food sources are relatively specialized. The best natural sources are fermented soy products (such as natto). Certain cheeses, animal liver, egg yolks, and some meats also contain certain amounts of vitamin K2. However, with changes in modern diets, the intake of these vitamin K2-rich foods is generally insufficient, resulting in a gap in people's vitamin K2 intake.

How Vitamin K2 bulk Works

After calcium enters the body, it's absorbed from the small intestine and enters the bloodstream. However, calcium in the bloodstream can easily "get lost." Besides needed parts like bones and teeth, it can also be mistakenly deposited in the cardiovascular system, kidneys, and other soft tissues, leading to organ calcification and functional decline. Examples include cardiovascular calcification, kidney stones, and arteriosclerosis. Vitamin K2 bulk selectively deposits calcium in the bones, thus promoting bone health. Furthermore, vitamin K2 helps calcium ions in the blood settle in the bones, preventing them from accumulating in the blood vessels, thus preventing the symptoms of arteriosclerosis. Therefore, vitamin K2 plays a crucial physiological role in bone health.

YTBIO: Providing High-Quality Vitamin K2 Bulk And Services

High-quality nutritional supplements are crucial to your health journey. YTBIO specializes in providing high-quality Vitamin K2 bulk.

Why choose YTBIO? We hold the following certifications:

- cGMP, ISO9001, and ISO22000 certifications ensure rigorous quality control throughout the entire process;

- BRC and HACCP system certifications ensure product safety and reliability;

- EU and NOP organic, kosher, and halal certifications meet various global standards and dietary requirements.

We specialize in the research, development, and production of natural plant extracts, cosmetic active ingredients, and health foods. We primarily produce plant extracts, health food ingredients, and a variety of end-use products, including capsules, softgels, granular capsules, gummies, tablets, and solid beverages. Our production facilities and equipment meet national standards, and our production processes strictly adhere to GMP requirements. If you have any questions, please feel free to contact us at sales@sxytorganic.com.

Vitamin K2 BulkVitamin K2 Bulk

Physiological Functions of Vitamin K2 Bulk

1. Vitamin K2 Maintains Bone Health

Activates Osteocalcin: K2 activates this protein, secreted by osteoblasts, which "grabs" calcium from the blood into the bones, thereby increasing bone density.

Works synergistically with Vitamin D: Vitamin D promotes calcium absorption, while K2 ensures its precise delivery. Both are essential.

Vitamin K2 Bulk

Vitamin K2 increases bone density, improves bone quality, bone strength and collagen production

2. Cardiovascular Protection

In addition to bone health, Vitamin K2 bulk also plays a crucial role in cardiovascular health, particularly in mitigating vascular calcification. This is why vitamin K2 supplementation is particularly important for middle-aged and elderly individuals.

Activation of Matrix Gla protein (MGP): MGP is a potent inhibitor of vascular calcification, but requires vitamin K2 for activation. In the absence of vitamin K2, MGP becomes inactive, leading to calcium deposition in the blood vessel walls.

3. Regulating Coagulation Function

Vitamin K2 participates in the synthesis of coagulation factors and is crucial for maintaining normal coagulation function. It plays a particular role in preventing and treating vitamin K deficiency bleeding in neonates and coagulation disorders in adults.

4. Other Benefits

Improving Blood Glucose Metabolism: It may help reduce the risk of diabetes by promoting insulin secretion and increasing insulin sensitivity.

Neuroprotection: It supports nervous system health, possibly through antioxidant and anti-inflammatory mechanisms.

Liver Protection: It helps strengthen the liver's detoxification function and slow the progression of cirrhosis.

Applications of Vitamin K2 Bulk

Nutritional Supplementation

Vitamin K2 is widely used in dietary supplements. It can be consumed naturally through foods like natto, cheese, and animal liver, or supplemented with vitamin K2 soft capsules or combination preparations.

Bone Health

Vitamin K2 activates osteocalcin and matrix Gla protein, promoting the targeted deposition of calcium ions in bones and improving bone density. It is clinically used to prevent and treat osteoporosis, and its effectiveness is even greater when combined with vitamin D3. Supplementation can slow bone loss in postmenopausal women and the elderly.

Cardiovascular Protection

It reduces the risk of arteriosclerosis by inhibiting vascular calcification. Long-term, moderate supplementation may reduce coronary artery calcium score and benefit cardiovascular health in patients with hypertension and diabetes.

Coagulation Maintenance

As a coenzyme in the synthesis of coagulation factors II, VII, IX, and X, it participates in normal coagulation. Vitamin K1 injections in newborns can prevent bleeding disorders, and adults can consume it through green leafy vegetables and fermented foods.

K2 MK7 and K2 MK4:What's the difference?

Vitamin K2 bulk comes in several forms, the most common of which are MK-4 and MK-7.

Vitamin K2 Bulk

Source Differences

MK-4 primarily comes from animal foods (such as eggs, liver, and meat), though the body can also convert plant-based K1 into MK-4.

MK-7 is produced by bacterial fermentation and is abundant in fermented foods such as natto, cheese, and sauerkraut.

Activity and Half-Life

MK-4 has a short half-life of only a few hours, acting quickly but not maintaining high levels over time.

MK-7 has a half-life of up to three days, maintaining more stable levels in the body and more effectively activating proteins like osteocalcin.

Biological Actions

MK-4 is widely distributed in the brain, pancreas, and arteries and may have additional specialized physiological functions.

MK-7 reaches the bones and liver more efficiently, providing a more stable supply of K2 throughout the body.

Supplement Preference

MK-7 is typically taken once daily and is highly stable. Studies have shown its long-term benefits for bone and cardiovascular health.

MK-4 works quickly but requires frequent dosing; high-dose MK-4 (45 mg) is used in Japan to treat osteoporosis.

MK4 vs MK7

MK4 (Menadione-4)

MK7 (Menadione-7)

Source

Animal foods (egg yolk, liver), synthetics

Fermented foods (natto, cheese)

Half-life

Short duration (1-2 hours)

Long-lasting effect (approximately 72 hours)

Dosage frequency

Requires multiple daily supplements (e.g., 3 times/day)

Once daily is sufficient

Bioavailability

Fast absorption but rapid metabolism

Standard absorption and prolonged blood retention

Research evidence

Promotes bone health

More robust evidence for cardiovascular protection

What Are Some Common Combinations For Taking Vitamin K2 Bulk?

1. Vitamin K2 with calcium supplements

Benefits: When the body is deficient in vitamin K2 bulk, calcium deposition can be somewhat random, potentially erroneously deposited in areas like blood vessels. Vitamin K2 activates matrix glutamate protein (MGP) and osteocalcin, preventing calcium ions from depositing on blood vessel walls and other organs, thereby promoting calcium deposition in bones. Combining vitamin K2 with calcium supplements can improve calcium absorption.

2. Vitamin K2 with cardiovascular medications

Benefits: Vitamin K2 activates matrix glutamate protein, preventing calcium deposition and calcification in areas like blood vessels, preventing arteriosclerosis and reducing the formation of calcified arterial plaques.

3. Vitamin K2 with antidiabetic medications

Benefits: Vitamin K2 improves pancreatic arteriosclerosis, boosting the pancreas's blood and oxygen supply, thereby enhancing insulin secretion.

4. Vitamin K2 with liver protection tablets

Benefits: Vitamin K2 can activate liver stem cells and promote liver cell regeneration. Used in combination with liver protection tablets, it soothes the liver and regulates qi, strengthens the spleen and aids digestion, and lowers transaminases.

Precautions: Consult a physician before use in all cases.

YTBIO has own factory and R&D team, dedicated to providing you with high-quality Vitamin K2 bulk and services. If you have any questions or needs, please contact us and we will respond to you as soon as possible.