Tirzepatide Powder Bulk

Tirzepatide Powder 98% Raw Material Supplier

YTBIO provides 98% pure Tirzepatide Powder. Please contact us for product information and the latest pricing.Tirzepatide Powder Bulk is a synthetic peptide active pharmaceutical ingredient (API), belonging to the dual receptor agonists of GIP (glucose-dependent insulinotropic peptide) and GLP-1 (glucagon-like peptide-1).

Tirzepatide acts simultaneously on both GIP and GLP-1 receptors. Both of these gut-derived hormone pathways are involved in glucose-dependent insulin secretion, appetite regulation, and energy metabolism. Compared to selective GLP-1 receptor agonists, tirzepatide, by acting on both receptors simultaneously, forms a unique dual mechanism of action, making it an important component in research on diabetes, obesity, and metabolic-related diseases. Clinical studies have shown that tirzepatide has significant effects in improving glycemic control and reducing weight.​​​​​​​

Product Details

Why Can Hypoglycemic Ingredient Also Help Lose Weight?​​​​​​​

Not all hypoglycemic agents contribute to weight loss. The weight-loss effect of tirzepatide is closely related to its activity on the GIP and GLP-1 receptor pathways.

The GLP-1 signaling pathway can affect appetite and food intake, and the combined GIP/GLP-1 mechanism may produce broader metabolic effects. Therefore, clinical trials have investigated not only the efficacy of tirzepatide in glycemic control but also its application in weight management.

The trial provided clinical evidence for the weight-loss effect of tirzepatide in obese or overweight adults without type 2 diabetes.

Tirzepatide Powder Bulk has been extensively evaluated in multiple clinical development programs. These studies have explored the effects of teirapatide on weight and glycemic control in different populations.

SURMOUNT-1: Weight Management Study

SURMOUNT-1 was a clinical study in overweight or obese adults, enrolling 2,539 participants without type 2 diabetes. The study lasted 72 weeks and primarily assessed the effects of different doses of teirapatide on weight change.

Published data showed that all experimental doses of teirapatide demonstrated a significant trend toward weight loss compared to placebo, with the 15 mg dose group showing an average weight loss of approximately 20.9% at 72 weeks, compared to an average weight loss of approximately 3.1% in the placebo group.

SURMOUNT-2: Type 2 Diabetes Study

SURMOUNT-2 further evaluated the effects of teirapatide on weight in overweight or obese adults with type 2 diabetes. This study included 938 participants, followed for 72 weeks, and compared the results of the teirapatide 10 mg, 15 mg, and placebo groups.

Publicly available data showed that at 72 weeks, the mean weight loss in the 10 mg and 15 mg teirapatide groups was approximately 13.4% and 15.7%, respectively, while the mean weight loss in the placebo group was approximately 3.2%.

This study further provides data support for metabolic studies of teirapatide in overweight or obese diabetic patients.

Glycemic Control Related Studies

In addition to weight management studies, clinical applications of teirapatide also focus on its glycemic control effects. The SURPASS-AP-Combo study included 917 patients with type 2 diabetes, primarily from China, South Korea, Australia, and India, with 763 from China. This study compared glycemic control with different teirapatide dosing regimens and once-daily glargine insulin therapy.

Results showed that during the 40-week treatment period, glycated hemoglobin (HbA1c) was significantly reduced from baseline in all Tirzepatide dose groups. A high proportion of patients with HbA1c < 7.0% was observed in all Tirzepatide dose groups.

These publicly available research results demonstrate that the dual GIP/GLP-1 receptor agonist mechanism of Tirzepatide is not only of great interest in weight management but also holds significant research value in type 2 diabetes and glycemic control studies.

*The above information is compiled based on publicly available clinical research data and is for product and research reference only.Data source: SURMOUNT-1 clinical trial (NEJM 2022)

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