2-Deoxy-D-Glucose Powder
Package: 25Kg/barrel
CAS: 154-17-6
Molecular Formula: C6H12O5
Molecular Weight: 164.16
Inventory: In Stock
Certification: ISO9001, ISO22000, Kosher, Halal, HACCP
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Product Introduction
What is 2-Deoxy-D-Glucose?
2-Deoxy-D-Glucose Powder(2-DG) is an anti-metabolite of D-glucose, which is widely found in nature, especially in bacteria and actinomycetes. It has an important metabolic regulatory role in organisms, especially in the study of the molecular mechanism of simulating calorie restriction, showing potential application value. It has the effects of interfering with the synthesis of virus-specific glycoproteins, inhibiting herpes simplex virus, RAN and DNA enveloped viruses. Since it has no toxic side effects, it has a wide range of applications in the fields of medical health products, anti-aging cosmetics and life science research, and has good development prospects.
Features
Structural and functional differences: 2-DG is similar to glucose in structure, but the 2-OH group is replaced by a hydrogen atom, which makes it unable to be further metabolized, accumulates in cells, and inhibits various enzymes in the glycolysis pathway in a competitive and non-competitive inhibition manner, thereby blocking the glycolysis process and causing cell energy depletion.
Anti-aging potential: By simulating calorie restriction, it helps slow tumor growth and improve the survival rate of the body.
Biological activity: It can compete with glucose in cells to bind to the glucose transporter on the cell membrane, thereby inhibiting the cell's uptake and utilization of glucose.
Product Details Table
Product Name | 2-Deoxy-D-Glucose |
CAS | 154-17-6 |
Molecular Formula | C6H12O5 |
Molecular Weight | 164.16 |
EINECS | 205-823-0 |
Melting Point | 146-147°C (lit.) |
Specific Rotation | 45.5º (c=2, H2O) |
Boiling Point | 211.61°C (roughestimate) |
Density | 1.1738 (roughestimate) |
Storage Conditions | 2-8°C |
Function
Antiviral and antibacterial
2-Deoxy-D-Glucose Powder has the ability to inhibit viral infection, including human rhinovirus, coronavirus, etc., and reduces viral proliferation by interfering with the metabolic process of the virus. In addition, it can inhibit the growth of bacteria and mycoplasma.
Anti-aging potential
Studies have shown that it can mimic the effects of caloric restriction, activate related molecular signaling pathways, enhance antioxidant capacity, and prolong the lifespan of certain model organisms.
Anti-metabolism
It can interfere with the synthesis of virus-specific glycoproteins and effectively inhibit the proliferation of herpes simplex virus, RNA and DNA enveloped viruses, and breast cancer cells.
Anti-inflammatory
It can block glucose metabolism and reduce the production of inflammatory factors, thereby having an anti-inflammatory effect. This effect is particularly evident in the ketogenic state, and 2-DG can quickly reduce the level of inflammation.
Promote neural regeneration and functional recovery
In Alzheimer's disease (AD) and ischemic stroke models, it has shown the effects of improving memory and promoting functional recovery. These effects may be related to reducing N-linked glycosylation, increasing endoplasmic reticulum stress, and activating the BDNF gene.
2-DG promotes motor function recovery after stroke and improves cognitive function in AD models
2-DG is a glucose analog that can simulate glucose restriction and induce the transcription of the plasticity-promoting factor Bdnf in the brain without ketosis. Enhances memory function in Alzheimer's disease models and functional recovery in ischemic stroke models. Mechanistically, it increases the transcriptional expression of Bdnf by reducing N-glycosylation-induced endoplasmic reticulum stress and ATF4 activity. This study shows that intermittent fasting, as a method of simulating glucose restriction, can stimulate neural plasticity through the adaptive endoplasmic reticulum stress pathway, thereby significantly improving cognitive function in Alzheimer's disease models and promoting the recovery of neural and motor functions after ischemic stroke.
2-DG treatment after stroke improves sensory and motor function
2-DG alleviates learning and memory impairment in 5×FAD mice
Application direction
Health products
2-Deoxy-D-Glucose Powder has anti-aging effects and can be used to make health products to promote human health.
Food
It can be used as a food additive to improve the texture and taste of food.
Cosmetics
It has anti-aging effects and can be used to prepare anti-aging cosmetics.
Medicine
It is used for the treatment of antiviral, antibacterial and diabetes diseases.
Formulation Of 2-Deoxy-D-Glucose Powder
Capusle Formulation
Tablet Formulation
Solid Drink Formula
Certificates
YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality 2-Deoxy-D-Glucose Powder and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.