Bee Melittin
Specifications: 40% 70%
CAS: 20449-79-0
Appearance: Light brown powder
Molecular Formula: C131H229N39O31
Molecular Weight: 2846.46
Shipping Speed: 3-5 days
Certification: cGMP,ISO22000,ISO9001,EU&NOP Organic Certificate,Kosher,BRC,Halal,HACCP
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Are You Familiar With Bee Melittin?
Bee Melittin, also known as melittin, Bee Venom or Bee Venom Peptide, is the primary component and major bioactive substance in bee venom, accounting for approximately 40% to 50% of its dry weight. It is a polypeptide composed of 26 amino acid residues. It is one of the most potent anti-inflammatory substances and also possesses antibacterial, anti-radiation, and antiviral properties.
Mechanism of Action
·Lysis of Pathogens, Elimination of Infection Sources
With its unique structure, melittin can directly penetrate the cell membranes of bacteria and other pathogens like a "molecular drill," creating pores in the membranes, leading to leakage of cellular contents and ion imbalance, ultimately causing the pathogen's death due to structural disruption. This physical membrane-destroying effect enables it to be broadly and effectively effective against a wide range of microorganisms, including drug-resistant bacteria (such as MRSA), rapidly eliminating the source of infection that causes inflammation.
·Inhibiting Excessive Inflammatory Responses
At concentrations below those that directly kill cells, melittin can penetrate deep into cells and precisely regulate multiple key inflammatory signaling pathways. By inhibiting core "inflammatory switches" like NF-κB and MAPK, it reduces the production and release of pro-inflammatory factors like TNF-α and IL-6 at the source. Simultaneously, by interfering with the JAK/STAT pathway, it promotes apoptosis in abnormally inflamed cells and activates the body's own antioxidant enzymes, such as SOD. These combined effects create a synergistic anti-inflammatory and antioxidant effect, systematically alleviating tissue inflammatory damage.
·Bidirectional Immune Regulation
In addition to its direct antimicrobial and anti-inflammatory effects, Bee melittin can intelligently modulate the immune system itself. By influencing Toll-like receptor (TLR4) signaling and T cell differentiation, it can both suppress excessive immune attacks (helping to alleviate autoimmune diseases) and, in certain circumstances, enhance the body's immune surveillance and response to tumor cells. This unique "bidirectional regulation" function helps restore an imbalanced immune state to normal.
YTBIO: Providing High-Quality Bee Melittin and Services
Why choose YTBIO? We hold the following certifications:
- cGMP, ISO9001, and ISO22000 certifications ensure rigorous quality control throughout the entire process;
- BRC and HACCP system certifications ensure product safety and reliability;
- EU and NOP organic, kosher, and halal certifications meet various global standards and dietary requirements.
We specialize in the research, development, and production of natural plant extracts, cosmetic active ingredients, and health foods. We primarily produce plant extracts, health food ingredients, and a variety of end-use products, including capsules, softgels, granular capsules, gummies, tablets, and solid beverages. Our production facilities and equipment meet national standards, and our production processes strictly adhere to GMP requirements. If you have any questions, please feel free to contact us at sales@sxytorganic.com
Bee Melittin's Multiple Benefits
Powerful Anti-Inflammatory Effects
Bee melittin has exceptional anti-inflammatory properties, up to 100 times more potent than hydrocortisone. It effectively controls inflammation by inhibiting leukocyte migration, reducing vascular permeability, and reducing prostaglandin synthesis, demonstrating significant therapeutic benefits for inflammatory diseases such as rheumatoid arthritis and neuritis.
Antibacterial and Antiviral Effects
Melittin inhibits a wide range of Gram-positive and Gram-negative bacteria, and is particularly effective against antibiotic-resistant strains (such as Staphylococcus aureus). It also combats various viruses, including influenza and herpes, by destroying viral envelopes and inhibiting viral replication.
Effective Relief of Nerve Pain
Melittin has potent analgesic properties, approximately 40% of the potency of morphine. By acting on the central nervous system, it raises the pain threshold and reduces pain sensitivity, demonstrating its effectiveness in treating intractable neuralgia, such as trigeminal neuralgia and sciatica.
Regulating Cardiovascular Function
Bee melittin can enhance the body's tolerance to radiation, improving the survival rate of irradiated animals by protecting hematopoiesis and regulating immunity. Furthermore, it can regulate blood pressure and improve microcirculation, providing a therapeutic aid for cardiovascular diseases such as hypertension and myocarditis.
Bee Melittin – Its Anti-inflammatory Effect In Skincare
With the increasing popularity of aesthetic procedures, post-operative recovery has become a crucial factor in determining the success of these procedures. Naturally derived melittin, with its remarkable anti-inflammatory and repairing properties, has gradually become a core ingredient in high-end aesthetic repair products. Within the aesthetic field, melittin's diverse properties are being cleverly utilized for post-operative recovery, anti-aging treatments, and the improvement of various skin conditions.
Anti-inflammatory mechanism of bee melittin
Bee Melittin's Benefits for Skin
·Powerful Anti-Inflammation, Accelerating Postoperative Recovery
Melittin precisely targets key pathways of the inflammatory response, rapidly inhibiting the release of multiple pro-inflammatory factors. This effectively reduces post-operative discomfort, including redness, swelling, heat, and pain, and creates a favorable environment for tissue repair.
·Antibacterial Protection, Protecting Wound Health
Bee melittin can physically disrupt bacterial cell membranes, demonstrating potent inhibitory effects against common pathogens such as Staphylococcus aureus and Propionibacterium acnes, effectively reducing the risk of post-operative wound infection.
·Stimulates collagen production and improves repair quality
Melittin uniquely stimulates the synthesis of both type I and type III collagen and promotes elastic fiber regeneration, accelerating dermal reconstruction, improving skin texture and repair.
·Relieves postoperative discomfort
By reversibly blocking excessive neuromuscular signaling, melittin effectively relieves abnormal postoperative tingling and itching, making it particularly suitable for those with sensitive skin and rosacea.
·Improves microcirculation
Bee melittin promotes local blood circulation, helping to reduce postoperative bruising while also delivering more oxygen and nutrients to the skin, allowing it to quickly regain its healthy, radiant glow.
YTBIO has own factory and R&D team, dedicated to providing you with high-quality Bee melittin and services. If you have any questions or needs, please contact us and we will respond to you as soon as possible.
FAQ
Q: What certifications do you hold?
A: We prioritize product quality and safety, and our production facilities hold several top international certifications, including:
· cGMP
· ISO9001 and ISO22000
· BRC
· HACCP
· EU and NOP organic certifications
· Kosher certification
· Halal certification
Q: Do you provide third-party test reports (COAs) for your products?
A: Of course. We provide a COA with every batch.
Q: Do you offer custom products and technical support?
A: Yes, we have a strong R&D team. In addition to standard products, we can also provide customized dosage forms and customized packaging to meet your specific needs.
Our technical team is always ready to provide comprehensive technical support, including product application and formulation advice.