Natamycin Powder

Natamycin Powder

CAS: 7681-93-8
Molecular Formula: C33H47NO13
Molecular Weight: 665.73
EINECS: 231-683-5
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Product Introduction

What is Natamycin?

Natamycin Powder, also known as pimaricin, is a natural antifungal compound produced by the fermentation of Streptomyces. It can not only widely and effectively inhibit the growth of various molds and yeasts, but also inhibit the production of mycotoxins. At the same time, it has a better inhibitory effect on vigorous living cells, and requires a higher concentration to inhibit dormant cells, but it cannot inhibit the activity of bacteria and viruses. It can also be widely used in food preservation and antifungal treatment.

As a natural, broad-spectrum, and highly effective polyene macrolide antifungal agent, it has been used in medical treatment, food, feed, and grain storage, especially in the preservation of food raw materials and the preservation of finished products, showing good prospects.

Natamycin Powder

Product Details List

Product Name Natamycin
CAS 7681-93-8
Molecular formula C33H47NO13
Molecular weight 665.73
EINECS 231-683-5
Boiling point 952.2 ℃
Water solubility almost insoluble
Melting point 2000C (dec)
Density 1.0 g/mL at 20 °C(lit.)
Solubility Soluble in DMSO
Acidity coefficient (pKa) pKa 4.6 (50% aq. MeOEtOH) (Uncertain); 8.35 (Uncertain)

Features

Highly effective antibacterial ability: It has strong inhibitory power against molds and yeasts, and can achieve good anti-mold and fresh-keeping effects at a lower dosage, effectively extending the shelf life of food.

Broad spectrum: In addition to being effective against fungi, it is ineffective against bacteria and viruses, making it have wide application potential in food, medicine, feed and other fields.

Stability: It shows good stability in the pH range of 3 to 9, but its antibacterial activity will decrease in strong acid or alkaline environments. In addition, it is not suitable for high-temperature treatment, and its antibacterial activity will be rapidly lost when it exceeds 100°C.

Safety: It is harmless to the human body, difficult to be absorbed by the human digestive tract, and it is difficult for microorganisms to develop resistance to it, so it is relatively safe to use.

Solubility: It is slightly soluble in water and methanol, but soluble in dilute acid and glacial acetic acid, and difficult to dissolve in most organic solvents. This property helps ensure that the preservative only stays on the surface of the food and does not penetrate into the food.

Benefits

Safety and environmental protection: Natamycin Powder is easily degraded in the natural environment and has less pollution to soil and water sources.

Antifungal activity: It has a strong inhibitory effect on a variety of yeasts and filamentous fungi, and can effectively fight fungal spores such as gray mold and rust.

Improve crop immunity: It can stimulate the crop's own immune system, enhance resistance to pathogens, reduce the frequency of diseases, and help reduce the use of chemical pesticides.

Antibacterial synergism: When used in combination with other antimicrobial agents such as potassium sorbate, calcium propionate and nisin, it can expand the antibacterial spectrum and improve the preservative effect, while reducing the dosage and improving safety.

Antibacterial Mechanism

It relies on its lactone ring structure to interact with sterol compounds on the fungal cell membrane to form antibiotics-sterol compounds, thereby destroying the structure of the fungal cytoplasmic membrane. The hydrophilic part of the macrolide forms water holes on the membrane, damaging the permeability of the cell membrane, and then causing the exudation of amino acids, electrolytes and other substances in the bacteria, resulting in the death of the bacteria. When sterol compounds do not exist on the cell membrane of certain microorganisms, natamycin has no effect on them, so it only inhibits fungi and has no antibacterial activity against bacteria and viruses.

Natamycin Powder

Application Areas

Food
It is widely used in the food industry to prevent dairy products, meat products, pastries, juices, wines and other foods from spoiling due to the growth of mold and yeast. It can effectively extend the shelf life of food and maintain the quality and taste of food.

Cosmetics
It is used as a preservative in cosmetics to prevent cosmetics from being contaminated by microorganisms during storage and use, and to ensure the quality and safety of cosmetics.

Medicine

In the field of medicine, it is used to treat various infections caused by fungi, such as fungal keratitis, conjunctivitis, blepharitis and other eye infections, as well as fungal infections of the skin and mucous membranes. It inhibits the growth and reproduction of fungi by destroying the structure of fungal cell membranes.

Agriculture
It is also used as a feed additive to improve animal immunity, prevent animal diseases and promote animal growth. In agriculture, it can also be used to treat crops to prevent diseases caused by fungi.

Certificates

YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Natamycin Powder and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.

Natamycin Powder

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Natamycin Powder

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Natamycin Powder