Alpha Mangostin Powder
Source: Mangosteen Shell
CAS: 6147-11-1
Molecular formula: C24H26O6
Molecular weight: 410.46
Melting point:180-182°C
Boiling point:640.1±55.0 °C (Predicted)
Density: 1.265±0.06 g/cm3 (Predicted)
Storage conditions: 2-8°C
Appearance: BrownYellow Powder
Storage Conditions: Cool And Dry Place
Testing Method: HPLC
Shipping Speed:1-3 days
Certifications: ISO9001,ISO22000,Kosher,Halal,HACCP
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
SHAANXI YUANTAI BIOLOGICAL TECHNOLOGY CO., LTD.: Your Trusted Alpha Mangostin Powder Supplier
As a leading Alpha Mangostin Powder manufacturer and supplier, Shaanxi Yuantai Biotechnology Co., Ltd. provides premium extracts with strict quality control and international certifications. Our advanced equipment and professional team ensure that each batch of products has consistent potency and purity, making it the first choice for companies seeking reliable, high-quality pangostin powder.
Why Choose Our Alpha Mangostin Powder?
When you partner with SHAANXI YUANTAI BIOLOGICAL TECHNOLOGY CO., LTD., you're choosing:
- Consistently high-quality extracts with standardized potency
- Rigorous quality control measures and third-party testing
- Compliance with international standards and regulations
- Sustainable and traceable sourcing practices
- Competitive pricing for bulk quantities
- Expert technical support and formulation assistance
Introduction to Alpha Mangostin Powder
Alpha mangostin powder refers to the powder form of a compound called alpha mangostin extracted from mangosteen shell. Alpha mangostin is a ketone compound that has multiple biological activities, including antioxidant, anti-inflammatory, and anti-oxidant effects.
Functions of Alpha Mangostin Powder?
Anti-inflammatory
Alpha mangostin powder inhibits the activity of cyclooxygenase and sphingomyelinase, participates in regulating cell growth, differentiation, apoptosis and other processes, thereby playing an anti-inflammatory role.
Antibacterial
Alpha mangostin has strong antibacterial activity against methicillin and toluene penicillin-sensitive Staphylococcus aureus.
Antioxidant
Alpha mangostin powder has antioxidant activity, can inhibit the oxidation of low-density lipoprotein, and has potential benefits in combating cardiovascular disease and other chronic diseases.
Antioxidant effect
As a free radical scavenger, Alpha mangostin powder can protect low-density lipoprotein from oxidative damage, thereby reducing the risk of cardiovascular disease and other chronic diseases.
Anti-inflammatory and neuroprotective
In the nervous system, it exerts multi-target neuroprotective effects on diseases such as Alzheimer's disease, depression, autism, vascular dementia, and schizophrenia by inhibiting inflammatory response, anti-oxidative stress, and anti-neuronal apoptosis.
Protective effect of alpha mangostin powder in the nervous system
The protective effect of Alpha mangostin in the nervous system is mainly reflected in its multi-target pharmacological properties, which play a positive role in maintaining and restoring the health and function of the nervous system through different mechanisms.
Inhibition of inflammatory response: Alpha mangostin can inhibit the inflammatory response of the nervous system through multiple pathways, reduce the production and release of inflammatory factors, and thus protect neurons from inflammatory damage.
Anti-oxidative stress: As a potent free radical scavenger, a-mangostin can effectively neutralize oxidative stress products in the body and reduce oxidative stress damage to neurons. Anti-neuronal apoptosis: By inhibiting the related signaling pathways of neuronal apoptosis, a-mangostin can reduce neuronal death and protect the number and function of neurons.
Protective effect in specific diseases
Alzheimer's disease (AD)
Inhibition of the formation of Aβ fibers: It can inhibit the fibrosis and aggregation of Aβ proteins, thereby reducing the toxic effects of Aβ deposition on neurons.
Reduce the aggregation of Aβ protein: By binding to specific sites of Aβ protein, alpha mangostin can interfere with the aggregation of Aβ protein, further reducing its damage to neurons.
Reduce inflammatory damage: Regulate the activation state and behavior of microglia, reduce the production of inflammatory factors, and thus reduce inflammatory damage to the nervous system.
Anti-neuronal apoptosis: By increasing the activity and expression of heme oxygenase (HO)-1, It can produce anti-apoptotic effects and protect neurons from the threat of apoptosis.
Parkinson's disease
Antioxidant: In a variety of PD models, It exhibits significant antioxidant effects and can reduce the damage of oxidative stress to dopaminergic neurons.
Anti-inflammatory: By inhibiting the activation of microglia and the production of inflammatory factors, alpha mangostin can reduce the inflammatory response of the nervous system.
Anti-neuronal apoptosis: By regulating apoptosis-related signaling pathways such as p53-Bcl-2, alpha mangostin can reduce the apoptosis of neurons in PD models.
Anti-inflammatory effect of alpha mangostin powder
It exhibits significant anti-inflammatory effects, which are achieved through multiple pathways and mechanisms.
Inhibit inflammatory response
It can significantly reduce the secretion of various inflammatory mediators, such as prostaglandin E2 (PGE2), interleukin-1β (IL-1β), etc. These inflammatory mediators play a key role in the inflammatory response, and their reduction can help relieve inflammatory symptoms.
Alpha mangostin regulates inflammatory responses by inhibiting the Toll-like receptor 4 (TLR4)/nuclear factor-kB (NF-kB) signaling pathway and the MAPK (mitogen-activated protein kinase) inflammation-related signaling pathway. These signaling pathways play an important role in the initiation and maintenance of inflammatory responses, and their inhibition helps reduce inflammatory responses.
Antioxidative stress
Up-regulation and activation of antioxidant enzymes: Alpha mangostin can up-regulate the gene expression and secretion of antioxidant enzymes such as superoxide dismutase (SOD) and catalase (CAT), while activating the Nrf2-ARE signaling pathway and up-regulating anti-oxidant enzymes. Expression of oxidases HO-1 and NQO1. These antioxidant enzymes play an important role in scavenging free radicals and reducing oxidative stress.
Alpha mangostin can inhibit the production of reactive oxygen species (ROS), thereby reducing the damage to cells caused by oxidative stress.
Antibacterial
Alpha mangostin has inhibitory effects on a variety of pathogenic bacteria, including Staphylococcus aureus. It inhibits the growth and reproduction of pathogenic bacteria and reduces the invasion and infection of the body by pathogenic bacteria, thereby indirectly reducing the inflammatory response.
Application Fields
Medical field
Rheumatoid arthritis treatment: Use it and its self-microemulsification preparation technology to treat rheumatoid arthritis.
Alzheimer's disease treatment: Alpha-mangostin and its derivatives have been studied chemically and biologically in the treatment of Alzheimer's disease, showing the effects of inhibiting Aβ aggregation and immunosuppression.
Anti-leukemia and sepsis: Alpha-mangostin has a certain therapeutic effect on blood system diseases such as leukemia and sepsis.
Health care products field
Alpha-mangostin is widely used in the field of health care products, including but not limited to the treatment of digestive system diseases, blood system diseases, nervous system diseases, etc.
Treatment of diarrhea and anti-inflammatory effects: Alpha-mangostin is believed to have astringent and antidiarrheal effects and can be used to treat diarrhea. At the same time, it also has anti-inflammatory effects, which can reduce inflammatory reactions and relieve symptoms such as pain and swelling.
Anti-ulcer effect: This substance can promote the repair and regeneration of gastric mucosa, and help relieve the symptoms of digestive system diseases such as gastric ulcers.
Improved neuroprotective activity: Through structural optimization, Alpha-mangostin can reduce toxicity, enhance neuroprotective activity and the ability to penetrate the blood-brain barrier, and improve its drugability.
Certificates
YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.
Packaging and Shipping
We offer flexible packaging options to meet your specific requirements, from small quantities to bulk orders. Our efficient logistics network ensures timely delivery of your product, maintaining product integrity throughout the transportation process.
Our Company and Factory
We have our own in-house lab and work with professional third-party testing agencies to ensure that every batch of our products meets the highest quality standards.
Our dedicated R&D team is constantly exploring new applications and delivery methods for our products. We invest in cutting-edge technologies to ensure consistent quality and efficacy with every batch of our products, providing innovative solutions for your product development needs.
FAQ
Q: What is the shelf life of the product?
A: Our powder is properly stored in a cool, dry place away from direct sunlight and has a shelf life of typically 24 months.
Q: Can you provide custom formulations of it?
A: Yes, we do offer custom formulations to meet your specific needs. Please contact our technical team to discuss your requirements.
Contact Us
Ready to enhance your products with our premium Alpha Mangosteen Powder? Please contact our sales team at sales@sxytorganic.com to discuss your needs, request samples, or place an order. Let Shaanxi Yuantai Biotechnology Co., Ltd. be your trusted partner in bringing high-quality, innovative products to market.