Corydalis Yanhusuo Extract

What Is Corydalis Yanhusuo Extract?

Corydalis yanhusuo extract is a mixture of active ingredients extracted from the dried tubers of the poppy family plant Corydalis yanhusuo. The primary active ingredient is tetrahydropalmatine (THP), particularly its levorotatory isoform (L-THP). Corydalis yanhusuo extract and its main ingredient, tetrahydropalmatine, are used to relieve various pains, especially chronic dull pain and visceral pain. It is also used for sedation and sleep improvement. Corydalis yanhusuo extract is primarily used in pharmaceuticals, health supplements, beverages, and food additives. This plant contains alkaloids that can help relieve chest pain and is believed to have the ability to promote blood circulation.When you need high-quality Corydalis yanhusuo extract, YTBIO is your reliable source. We specialize in providing high-purity, highly bioavailable Corydalis yanhusuo extract. Its superior efficacy stems from meticulous attention to detail in every step of the raw materials and production process. Trust YTBIO for the reliable quality you expect.

Corydalis yanhusuo extract contains alkaloids, steroids, and organic acids, which exhibit diverse pharmacological effects.

Alkaloids such as tetrahydropalmatine, berberine, palmatine, coptisine, and dehydrocorydaline are the primary active ingredients in Corydalis yanhusuo that exert its medicinal effects.

Steroids such as β-sitosterol and stigmasterol.

Organic acids such as fumaric acid and malic acid.

YTBIO: Providing High-quality Corydalis Yanhusuo Extract And Services

Why choose YTBIO? We hold the following certifications:

- cGMP, ISO9001, and ISO22000 certifications ensure rigorous quality control throughout the entire process;

- BRC and HACCP system certifications ensure product safety and reliability;

- EU and NOP organic, kosher, and halal certifications meet various global standards and dietary requirements.

We specialize in the research, development, and production of natural plant extracts, cosmetic active ingredients, and health foods. We primarily produce plant extracts, health food ingredients, and a variety of end-use products, including capsules, softgels, granular capsules, gummies, tablets, and solid beverages. Our production facilities and equipment meet national standards, and our production processes strictly adhere to GMP requirements. If you have any questions, please feel free to contact us at sales@sxytorganic.com

Health Benefits of Corydalis yanhusuo Extract​​​​​​​

Corydalis yanhusuo extract, particularly its core ingredient, tetrahydropalmatine, is a unique and highly safe natural medicinal source. It successfully combines central analgesia with non-addictive properties, offering multiple benefits such as sedation and cardiovascular protection.

Analgesic Effect

This is the most classic and widely used effect of Corydalis yanhusuo. Its analgesic strength lies between that of antipyretic analgesics (such as ibuprofen) and central analgesics (such as morphine). Unlike opioid analgesics, long-term use has not been associated with significant dependence or addiction, a significant advantage. It is effective for a wide range of pain types, including chronic persistent pain, visceral colic, neuropathic pain, and inflammatory pain.

Clinical Applications:

Neuralgia: Clinical studies have shown that a daily oral dose of 75 mg of tetrahydropalmatine significantly relieved neuralgia in 78% of patients.

Dysmenorrhea and postpartum pain: It effectively relieves pain caused by uterine spasms. Headache and postoperative pain: It also demonstrates excellent analgesic effects.

Mechanism of Action:

It primarily works by blocking dopamine D1 receptors in the central nervous system.

It also modulates the release of multiple neurotransmitters, increasing the release of endogenous analgesics (such as enkephalins) and inhibiting the transmission of pain signals.

Sedation and Hypnosis

Analgesia and sedation often occur synergistically. Its mild sedative effect helps relieve tension and anxiety. Its hypnotic effect is effective, effectively shortening sleep onset and promoting deeper sleep.

Clinical Applications:

For patients with insomnia, taking 100-200mg of tetrahydropalmatine before bedtime can significantly aid sleep. A key advantage is that next-day residual effects (such as drowsiness, dizziness, and fatigue) are very rare, resulting in improved sleep quality.

Mechanism of Action:

Similar to its analgesic mechanism, it inhibits the central dopamine system, reducing the excitability of the cerebral cortex, thereby allowing the body to enter a state of quiet rest.

Cardiovascular Protection

This is a very important area of ​​modern research involving Corydalis yanhusuo extract. A double-blind clinical trial showed that a daily dose of 300-600 mg of tetrahydropalmatine significantly improved arrhythmias in patients with premature upper ventricular contractions, surpassing placebo.

Mechanism: By affecting ion channels (such as calcium and potassium channels) in myocardial cells, it prolongs the duration of the action potential and inhibits the excitability of ectopic pacemakers, thereby stabilizing the heart rhythm.

Corydalis yanhusuo extract can dilate coronary arteries, increasing blood and oxygen supply to the heart. It also lowers blood pressure and heart rate, reducing the workload on the heart.

In animal studies, dl-THP has been shown to reduce platelet concentration and inhibit thrombosis. By lowering blood pressure and protecting brain tissue, it may help prevent stroke and cerebral ischemia.

Digestive System Regulation

Mechanism of Action:

Inhibits gastric acid secretion: Reduces the amount and acidity of gastric acid.

Protecting the gastric mucosa: Strengthens the gastric mucosal barrier function, protecting against various damaging factors. Relieves smooth muscle spasm: It has an antispasmodic effect on spasmodic pain in visceral smooth muscles, such as those in the gastrointestinal tract and biliary tract.

These effects make it a potential adjunctive treatment for conditions such as gastric ulcers, gastritis, and irritable bowel syndrome.

Other potential effects

Anti-inflammatory effects: In addition to indirectly reducing inflammation through analgesia, its components can also directly inhibit the production of inflammatory mediators such as prostaglandins and leukotrienes.

Currently, tetrahydropalmatine is used clinically as a single chemical drug, primarily for the relief of headaches, menstrual pain, and tension-related insomnia. Future research will further explore its potential for broader applications in cardiovascular and cerebrovascular diseases, digestive system disorders, and other areas.

Are You Aware Of The Non-medicinal Applications Of Corydalis Yanhusuo Extract?

1. Health supplements: The immunomodulatory and anti-inflammatory components of Corydalis yanhusuo may be used in the development of health supplements to enhance immunity and reduce inflammation.

2. Cosmetics: The antioxidant components in Corydalis yanhusuo may be used in cosmetics to protect the skin from free radical damage and slow down skin aging.

Cosmetic Applications of Corydalis yanhusuo Extract

Specific Case Study:

The Guangzhou Mashanghui Cosmetics CRO team, led by Senior Engineer Chen Laicheng, has conducted in-depth research on the traditional Chinese medicinal herb Corydalis yanhusuo, successfully applying it to cosmetics, creating the star product "Body Soothing Massage Cream" and establishing a core technology patent. Its core application is "soothing." Specifically:

Modern scientific research has found that the root tuber of Corydalis yanhusuo is rich in various active ingredients, among which tetrahydropalmatine (l-THP) and dehydrocorydaline (DHCB) have been shown to have significant potential to soothe and relieve skin discomfort.

In cosmetics, it is used to alleviate discomfort caused by muscle tension and strain. For example, adding it to body massage creams, soothing serums, or skincare oils and massaging it around the neck, shoulders, and waist can help the skin feel relaxed and soothed.

To ensure its stable effectiveness in cosmetics, researchers employ several technical techniques. For example, by optimizing the extraction process to obtain a higher purity of the active ingredient, and utilizing specialized dispersion techniques to ensure its stability within the formula and effective penetration into the skin's target area.

Simply put, the use of Corydalis yanhusuo extract in cosmetics is an example of leveraging modern technology to integrate the wisdom of traditional Chinese medicine into daily skincare, aiming to provide a deeper, more direct soothing experience for the skin.

FAQ

Q1: What are the core specifications of your Corydalis yanhusuo extract?

A: Our standard specification for Corydalis yanhusuo extract is 98% tetrahydropalmatine (THP) content, verified by HPLC testing. We also offer customized specifications based on customer needs.

Q2: What are the main applications of Corydalis yanhusuo extract?

A: This product is widely used in dietary supplements and health supplements, often in health formulas that support mood, promote calmness, and relaxation. It has also been explored in botanical daily chemical products.

Q3: What is the minimum order quantity (MOQ) for ordering?

A: To meet the needs of diverse customers, we offer flexible options and support small trial orders. Please contact us for details.

Q4: How do you ensure product quality and stability?

A: Quality is the cornerstone of YTBIO. We implement comprehensive quality control from raw materials to finished products and maintain a comprehensive COA (Conformance Certificate of Approval) system. All products are manufactured in GMP-compliant facilities to ensure the purity, safety, and efficacy consistency of every batch.

Q5: What technical support documents can you provide?

A: Of course. Before and after your order, we will provide technical documentation, including COA (Conformance Certificate of Approval) and MSDS (Material Safety Data Sheet), upon request to support your product development and regulatory compliance efforts.

Q6: What international quality and safety certifications do you hold?

A: Yes, we are proud to have received numerous stringent international certifications, which form the cornerstone of our commitment to quality. Our core certifications include cGMP, ISO 22000, ISO 9001, EU & NOP Organic Certificate, Kosher, BRC, Halal, and HACCP.

These certifications are more than just certificates; they represent our unwavering commitment to ensuring that every batch of our products is reliable, safe, and globally marketable.