Hydroxytyrosol Powder

What is hydroxytyrosol?

Hydroxytyrosol is a natural phenolic compound and one of the most potent natural antioxidants known—its oxygen free radical scavenging capacity reaches 4,500,000 μmol TE/100g, approximately 10 times that of green tea and more than twice that of coenzyme Q10 and quercetin. Studies have shown that hydroxytyrosol plays a significant role in combating oxidative stress, improving mitochondrial function, and preventing smoking-induced macular degeneration by inducing biphasic enzyme systems, promoting mitochondrial synthesis, and protecting retinal pigment epithelial cells. It also has potential value in research on diseases related to mitochondrial dysfunction, such as diabetes and obesity.YTBIO supplies hydroxytyrosol from two sources: fermented hydroxytyrosol with a purity of 98%; and natural hydroxytyrosol available in 10% and 5% concentrations, obtained through extraction and concentration from olives. All our products are manufactured in strict accordance with international certification systems such as cGMP, FSSC2200, BRC, HACCP, HALAL, KOSHER, ISO9001, and ISO22000, providing you with raw materials ranging from high-purity monomers to natural-grade hydroxytyrosol.

COA OF Fermented hydroxytyrosol 98%：

What are the benefits?

Treat thrombosis, arteriosclerosis and regulate blood lipids

Pure hydroxytyrosol has anti-aggregation effect. When the concentration is 100 mg/L, it participates in regulating proteins and exerts anti-aggregation effect. It can inhibit the adhesion activity of platelets, which makes it effective in preventing the formation of thrombus. The reason why hydroxytyrosol can fight cardiovascular diseases is closely related to its inhibition of platelet aggregation. It can inhibit the synthesis of thromboxane B and increase the production of nitrous oxide, thereby achieving an anticoagulant effect. Hydroxytyrosol has a good anti-thrombotic, atherosclerotic and blood lipid regulating effect on the treatment of cardiovascular diseases and has a good therapeutic effect on cardiovascular diseases.

Anti-inflammatory effect

The effect of hydroxytyrosol on LPS-induced THP-1 cells significantly reduces the number of cells with NF-kB DNA-binding transcriptional activity, and inhibits the transcription of tumor necrosis factor-α-inducible epoxy cyclooxygenase-2 ( COX-2) and nitric oxide synthase (i-NOS) gene expression and the inhibition of COX-2 and iNOS are key to inhibiting inflammation, and further research on the anti-inflammatory mechanism is needed.

Anti-pathogenic microorganism effect

It has the characteristics of broad spectrum, and its activity against Gram-positive bacteria is also higher than that of Gram-negative bacteria. The antibacterial activity is not only strong against harmful bacteria in the intestines, but also against thermophilic lactobacilli and bifidobacteria. The effects on various other pathogenic microorganisms require further study.

Hypoglycemic effect

The hypoglycemic effects and mechanisms are gradually discovered and studied. The hypoglycemic effect of hydroxytyrosol can cause the loss of antioxidant enzyme activity, which is a fundamental solution to hyperglycemia and is a major discovery.

Prevention and treatment of cardiovascular and cerebrovascular diseases

It has obvious blood-lipid-lowering effect. It is also speculated that the effect of hydroxytyrosol in lowering blood cholesterol may be by delaying the lipid oxidation process and increasing the activity of antioxidant enzymes, thereby reducing serum cholesterol levels, triglycerides and low-density lipoprotein cholesterol.

Related experiments on the anti-inflammatory and anti-aging effects of hydroxytyrosol on human dermal fibroblasts (HDFs)

Bulk hydroxytyrosol powder is found in olive leaves and oil as oleuropein. The antioxidant and anti-inflammatory effects of hydroxytyrosol have been reported in the fields of food, medicine, pharmaceuticals and life sciences. However, it has not yet been studied in the field of skin biology. The researchers demonstrated this using a UVA-induced cellular senescence model in human dermal fibroblasts. Through this study, researchers demonstrate that hydroxytyrosol has anti-inflammatory and anti-aging effects on UVA-damaged human dermal fibroblasts. Researchers believe that hydroxytyrosol is fully worthy of use as a cosmetic material, which can effectively anti-inflammatory and delay cell aging on human dermal fibroblasts.

Skin aging is a phenomenon in which cells are unable to regenerate or function properly due to cell loss or functional degradation. Aging has multiple biological, chemical, and physical causes; skin aging due to continued exposure to ultraviolet radiation is known as cutaneous photoaging. Exposure of skin to high levels of UV rays results in direct cytotoxicity and subsequent apoptosis. When UV rays are irradiated onto cultured fibroblasts or living tissue, matrix metallopeptidase (MMP) expression increases and collagen production decreases; this ultimately damages the connective tissue in the dermis. Sustained exposure to UVA affects a wide range of organisms, not only damaging human dermal fibroblasts but also affecting cell survival and growth and inducing protein denaturation, pigmentation, and the production of reactive oxygen species. In addition, some research results show that UVA and UVB can damage DNA and produce reactive oxygen species, inducing apoptosis, which directly or indirectly causes inflammatory responses. If this reaction develops in the skin for a long time, inflammatory factors will be excessively secreted and destroy normal tissues and cells, thereby becoming a causative factor in diseases such as cancer, hypertension, diabetes, and heart disease. In recent years, people have been actively researching natural active ingredients and traditional medicines to treat stubborn skin diseases and inhibit the chronic development of inflammatory skin diseases. These studies are used as a reference for the production of cosmetics and nutraceuticals.

In recent years, olives have been widely studied and utilized in many fields. In addition to their antioxidant effects, they can strengthen the immune system and increase energy levels. They are reported to be effective in treating respiratory diseases and skin diseases. Wound infections and relief of cold symptoms. Olive leaf is considered the best polyphenol complex, with a balance of super polyphenols such as hydroxytyrosol, tyrosol, caffeic acid and oleuropein. DHPEA-EDA (hydroxytyrosol), also found in olive oil, is reported to be more effective in protecting red blood cells from oxidative damage than other ingredients. Studies on the inflammatory effects of hydroxytyrosol discuss its anticancer effects on colon and breast cancer, its preventive and neuroprotective effects on osteoarthritis, and its inhibitory effects on oxidative stress and infectious mediators. Additionally, a skin-related study examined the photoprotective and anti-melanogenic effects of phenolic compounds contained in olive leaf extract on HaCaT cells.

Application

The applications of hydroxytyrosol are mainly concentrated in:

Food and health products: As a natural antioxidant, it is used to extend the shelf life of food; it is also added to health products, beverages, and yogurt to exert antioxidant, cardiovascular protection, and anti-inflammatory effects.

Cosmetics: Used for anti-aging skincare, protecting the skin from UV and free radical damage; in recent years, its applications have expanded to photoaging repair, scalp anti-aging, and regulating the skin's microecology.

Pharmaceuticals: It has shown therapeutic potential in neurodegenerative diseases, improving vascular function, and lowering uric acid.

Hydroxytyrosol supplier

Yuantai Organic Bio is committed to providing customers with the highest-quality pure hydroxytyrosol powder and services so that every consumer can enjoy natural, healthy, and high-quality food. If you have any inquiries or needs about our products, please feel free to contact us, and we will reply to you as soon as possible.

Tel:86-029-86478251 / 86-029-86119593
Whatsapp:8617782577059
Email:sales@sxytorganic.com
Office Add: No.801, Building 3, Dahua Shuzhi Industrial Park, Tiangu 6th Road, Yanta District, Xi 'an, Shaanxi，China.

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