Bulk Lime Extract

Introduction to Bulk Lime Extract

The main source of Bulk Lime Extract is the fruit of the lime plant of the Rutaceae family. Limes are mostly grown in hills, low mountains and along rivers and lakes with plenty of sunshine and warm and humid climate. They like warm, humid and sunny climates.Limes are rich in nutrients, containing protein, fat, dietary fiber, carbohydrates, carotene, thiamine, riboflavin, niacin, ascorbic acid, vitamin E, vitamins and a large number of trace elements, etc., as well as hesperidin, naringin, naringin, limonin, narcotine, citric acid, malic acid, etc. The peel contains volatile oil and more than 70 active substances.This extract is widely used in food, health care, medicine and cosmetics.

Properties: brown-yellow powder

Solubility: easily soluble in water and soluble in some organic solvents.

Production method
Lime extract is spray-dried or freeze-dried to make a powdered product.

YTBIO provides you with high quality Bulk Lime Extract Hesperidin

Main ingredients of Bulk Lime Extract

Flavones: such as hesperidin, naringin, etc., have antioxidant, anti-inflammatory, anti-allergic effects, and can also enhance vascular elasticity and reduce vascular permeability.

Alkaloids: such as synephrine, which is a sympathomimetic amine that can promote metabolism, contract the arrector pili muscles, and temporarily shrink the pores, thereby playing a role in oil control and astringency.

Other nutrients: It also contains protein, fat, dietary fiber, carbohydrates, carotene, thiamine, riboflavin, niacin, ascorbic acid, vitamin E, vitamin C and a large amount of trace elements, etc

Effects of Bulk Lime Extract

Bulk Lime extract has a variety of benefits, here are some of the main applications:

Antioxidant: Rich in flavonoids such as hesperidin and naringin, it can remove free radicals and protect cells.

Anti-inflammatory: Inhibits inflammatory mediators and relieves inflammatory reactions such as arthritis and gastroenteritis.

Antibacterial: Inhibits bacteria and fungi, assists in the treatment of infections, and can be used as a natural preservative.

Gastrointestinal regulation: Promotes digestion, relieves constipation, bloating, and relieves gastrointestinal spasm pain.

Cardiovascular protection: Lowers cholesterol, improves vascular function, and reduces the risk of arteriosclerosis.

Other effects: Analgesia, skin care and whitening (improves uneven skin tone and fades spots).

Application of Bulk Lime Extract

Food industry:natural spices and flavorings (beverages, candies, baking); nutritional enhancers (antioxidants, vitamins).

Medical field:stomach and digestion, anti-inflammatory and antibacterial, cardiovascular protection (lowering cholesterol and blood pressure).

Cosmetics:antioxidant skin care (anti-damage, brightening skin); hair care (scalp health, enhanced luster).

Other uses:feed additives (anti-oxidation, appetite); daily chemical products (soap, shower gel fragrance).

Due to its versatility and natural origin, Bulk lime extract has a wide range of application prospects in many industries.

Hesperidin:The Main Component of Bulk Lime Extract

Hesperidin, also known as tangerine peel glycoside and citrus glycoside, is a natural flavonoid compound in lime extract. In the field of traditional Chinese medicine, it is key and widely used, and now it is also shining in the field of modern skin care. In the study of the medicinal effects of citrus, its antioxidant and anti-inflammatory biological activities have gradually been revealed.Next, let us understand the important application of hesperidin in the field of skin care.

Active ingredients and effects

The active ingredients in hesperidin are mainly flavonoids, including hesperidin itself, naringin, neohesperidin, etc.

Hesperidin has an antioxidant effect, can remove free radicals and delay skin aging; can inhibit the release of inflammatory mediators and reduce skin inflammation; can also inhibit tyrosinase activity and reduce melanin production to whiten the skin.

Other flavonoid compounds can synergize with hesperidin in antioxidant and anti-inflammatory capabilities. They can also help regulate skin cell metabolism, promote skin renewal, and maintain skin health and vitality.

Antioxidant effect

Hesperidin can remove free radicals in the skin, prevent skin aging, reduce wrinkles, sagging and dullness, and maintain skin firmness and elasticity.

Mechanism of action:The phenolic hydroxyl group in the chemical structure of hesperidin has strong reducing properties, which can provide hydrogen atoms to combine with free radicals to form stable free radical intermediates, interrupt free radical chain reactions, and protect biological macromolecules in skin cells.

Whitening and freckle removal

Hesperidin can inhibit melanin production, reduce the formation of spots, lighten existing spots, and make the skin color even and white.

Mechanism of action: Hesperidin binds to the active center of tyrosinase, inhibits its activity, and reduces the conversion of tyrosine to dopaquinone; it can also regulate the melanocyte signal transduction pathway and reduce melanin synthesis and transport.

Anti-inflammatory and soothing

Hesperidin can reduce skin inflammatory reactions, relieve discomfort such as redness, swelling, itching, tingling, fever, etc., enhance skin resistance, and improve problems such as sensitive skin, acne, and sunburn.

Mechanism of action: Hesperidin inhibits the activation of inflammatory cells, reduces the release of inflammatory mediators, regulates skin immune function, promotes inflammation subsidence, and maintains skin barrier function.

Improves microcirculation

Hesperidin can promote blood circulation in the skin's microvessels, so that skin cells can obtain sufficient oxygen and nutrients, which is conducive to the discharge of metabolic waste, maintains healthy and rosy skin, improves dullness, and enhances vitality.

Blood Circulation

Mechanism of action: The antioxidant effect of hesperidin can maintain the function of vascular endothelial cells; the anti-inflammatory properties can reduce the impact of inflammation on microvessels; it may also regulate the vasoactive substances secreted by vascular endothelial cells.

Recommended combination

Hesperidin + niacinamide: niacinamide inhibits melanin transport, hesperidin inhibits tyrosinase, synergistic whitening, making the skin whiter, suitable for those with whitening needs.

Hesperidin + Ceramide: Ceramide builds the skin barrier, and hesperidin promotes cell repair and proliferation. The combination of the two strengthens the barrier function, which is beneficial to sensitive skin and skin with damaged barriers, and can relieve problems such as sensitivity.

Hesperidin + Retinol: Retinol stimulates collagen production and anti-aging, and together with hesperidin, accelerates cell renewal and anti-aging. It is suitable for people with anti-aging needs and good tolerance.

Synergistic Mechanism of Hesperidin and Vitamin C

The synergistic mechanism of hesperidin and vitamin C (ascorbic acid) when used together is reflected in multiple aspects, including anti-oxidation, vascular protection, anti-inflammation and metabolic regulation.

1. Antioxidant synergistic mechanism

Complementary effect of free radical scavenging:

As a water-soluble antioxidant, vitamin C directly removes free radicals (such as hydroxyl radicals and superoxide anions) in body fluids and protects cell membranes and cytoplasmic components. Hesperidin belongs to the flavonoids and can remove fat-soluble free radicals (such as lipid peroxidation free radicals) and inhibit the chain reaction of free radical generation. The combination of the two covers the antioxidant needs of water-soluble and fat-soluble environments, significantly improving the overall scavenging efficiency.

Reduction and regeneration of vitamin C and enhanced stability of hesperidin
Hesperidin can reduce the oxidative loss of vitamin C: in the antioxidant process, after vitamin C is oxidized to dehydroascorbic acid, hesperidin can be reduced and regenerated through electron transfer, prolonging the action time of vitamin C. The structural stability of hesperidin itself depends on vitamin C. The reducing property of vitamin C can protect the phenolic hydroxyl group of hesperidin from oxidation and maintain its biological activity.

Free radical scavenging mechanism

Synergistic effect of inhibiting lipid peroxidation:

Hesperidin can be embedded in the lipid bilayer of the cell membrane to block the lipid peroxidation chain reaction; vitamin C inhibits extracellular oxidative stress. The antioxidant effect of combined use on oil is significantly stronger than that of a single component and is dose-dependent.

2. Vascular protection and microcirculation improvement

Maintain capillary integrity

Hesperidin enhances the connection between endothelial cells, reduces vascular permeability, and reduces bleeding (such as gingival bleeding and retinal microvascular lesions). Vitamin C promotes collagen synthesis and strengthens the vascular basement membrane; hesperidin increases the cross-linking density of collagen fibers and jointly enhances vascular toughness.

Improve local blood flow and blood pressure regulation

Hesperidin dilates microvessels and inhibits angiotensin-converting enzyme (ACE), helping to lower blood pressure; vitamin C improves endothelial function by reducing oxidative stress and enhances the bioavailability of nitric oxide (NO). The combination of the two can significantly increase the microcirculation blood volume in the scalp, retina and other parts, and promote tissue repair (such as wound healing and hair follicle nutrition supply).

3. Anti-inflammatory and immune regulation synergistically

Inhibit the release of inflammatory mediators

Hesperidin downregulates the nuclear factor κB (NF-κB) pathway and reduces the production of pro-inflammatory factors such as TNF-α and IL-6; vitamin C inhibits neutrophil infiltration and histamine release. The combined use enhances the relief effect of chronic inflammation (such as arthritis and dermatitis).

Regulation of immune cell function

Vitamin C promotes T cell proliferation and phagocyte activity; hesperidin regulates Th1/Th2 immune balance and reduces allergic reactions (such as hay fever). Clinically, combined use can reduce the frequency of respiratory infections.

4. Synergy of iron metabolism and tissue repair

Promote iron absorption and utilization

Vitamin C reduces trivalent iron (Fe³⁺) to divalent iron (Fe²⁺), improving intestinal absorption rate; hesperidin inhibits hepcidin expression, increases the efficiency of serum iron transport to tissues, and jointly improves iron deficiency anemia.

Fe reduction

Collagen synthesis and wound repair

Vitamin C is a cofactor of proline hydroxylase, which directly drives collagen synthesis; hesperidin accelerates fibroblast migration by activating the TGF-β signaling pathway. Combined use can shorten wound healing time by more than 30% and reduce scar formation.

Hesperidin and vitamin C form a multi-level synergistic mechanism through complementary antioxidant, endothelial synergistic repair, dual inhibition of inflammatory pathways and iron metabolism regulation. This combination not only prolongs each other's active cycle, but also shows clinical advantages in microcirculation improvement and tissue repair, and is an effective strategy for nutritional intervention and chronic disease management.

YTBIO:Professional Bulk Lime Extract Manufacturer and Supplier

As a professional lime extract supplier, YTBIO is always committed to providing customers with high-quality natural ingredient solutions. We meet the diverse needs of the food, health care products, cosmetics and other industries with strict raw material screening, advanced production technology and scientific quality control. If you have any questions or needs about our Bulk lime extract, please contact us at sales@sxytorganic.com