Tanshinone powder

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YTBIO has been deeply involved in the plant extract industry for 12 years, supplying you with Tanshinone powder/tanshinone IIA, with a content ≥50% (HPLC). Our products have passed international certifications such as cGMP, FSSC22000, BRC, HALAL, KOSHER, ISO9001, and ISO22000, and support small-sample testing and flexible MOQ.

Test Result Table

What is Tanshinone?

Tanshinone powder is a fat-soluble phenanthrenequinone compound with antibacterial effects extracted from the traditional Chinese medicine Salvia miltiorrhiza (Lamiaceae plant Salvia miltiorrhiza root). From it, more than 10 types of tanshinone I, tanshinone IIA, tanshinone IIB, cryptotanshinone, and isocryptotanshinone are extracted. There are 5 tanshinone monomers, among which 5 monomers: cryptotanshinone, dihydrotanshinone II, hydroxytanshinone, tanshinone methyl ester, and tanshinone IIB, have antibacterial effects, as well as anti-inflammatory and cooling effects. Tanshinone IIA sodium sulfonate, the sulfonated product of tanshinone IIA, is soluble in water. Clinical trials have proven that it has significant effects in treating angina pectoris with few side effects. It is a new drug for the treatment of coronary heart disease. Tanshinone has many functions such as antibacterial, anti-inflammatory, promoting blood circulation and promoting wound healing. There are no obvious side effects after long-term use.

Tanshinone compounds are the main representatives of the fat-soluble components of Salvia miltiorrhiza and are widely distributed in the body. Together with salvianolic acid compounds, they have been confirmed to be the most important characteristic and active ingredients of Salvia miltiorrhiza. They have the functions of protecting vascular endothelium, improving microcirculation, and anti-inflammatory. , anti-infection and other effects. This type of compounds includes tanshinone I, tanshinone IIA, tanshinone IIB, dihydrotanshinone, cryptotanshinone, isocryptotanshinone, hydroxytanshinone, methyl salvinate, dihydrotanshinone I, tanshinone III, isotanshinone I, isotanshinone IIA, L-2 Hydrotanshinone I, Salvia quinone A, Salvia quinone B, Salvia quinone C and other ingredients. Among them, tanshinone IIA has the most prominent activity, and its content is about 0.1% to 0.9% of the salvia miltiorrhiza.

What are the Benefits?

1. Antibacterial effect

In vitro experiments, tanshinone has a stronger antibacterial effect on Staphylococcus aureus than berberine, and it also has an inhibitory effect on Mycobacterium tuberculosis H37RV strain (the minimum inhibitory concentration can reach less than 1.5 mg/mL) and two types of trichophyton.

2. Anti-inflammatory effect

Tanshinone administered by gavage to rats had significant anti-inflammatory effects. In the first stage of inflammation model, it has a significant inhibitory effect on the increase in capillary permeability caused by histamine; it has an inhibitory effect on acute joint swelling caused by egg white, carrageenan and dextran; it has an inhibitory effect on exudative formaldehyde peritonitis. effect. In the second stage of inflammation model, it has a significant inhibitory effect on the migration of white blood cells in mice caused by gelatin; it has a significant inhibitory effect on subacute formaldehyde joint swelling. For the third-stage inflammation model, the cotton ball granuloma test has no inhibitory effect (ie, no effect in the chronic stage). Tanshinone can reduce the levels of PGF2α and PGE in the blood of rats, which may be related to the anti-inflammatory mechanism of tanshinone.

3. Anticoagulant effect

Tanshinone has anticoagulant effects. The effect is stronger than that of protoethyl aldehyde.

4. Other functions

Tanshinone can improve the survival rate or extend the survival time of mice under hypobaric hypoxia. Tanshinone has anti-androgenic effects, reducing sebum production, and has anti-Propionibacterium acnes effects, reducing inflammation exacerbated by bacterial metabolism. Can be used to treat acne. Tanshinone has an antipyretic effect on rabbits with fever caused by typhoid vaccine. Experiments in mice indicate that tanshinone has mild estrogenic activity that acts through the ovaries.

5. The in vivo process was observed to see how tanshinone enters the liver and is excreted in the bile after duodenal administration. The results show that trace amounts of tanshinone can be measured in the bile after duodenal administration in rats in about 1 hour. The peak discharge is about 3 hours after administration. Tanshinones with different structures are excreted in the liver at different rates. In addition, the experiment also found that after using chloroform to extract tanshinone from bile, denatured protein was precipitated in the aqueous solution of bile, and there was a certain relationship between its content and different administration groups.

Application Direction

Tanshinone powder has unique biochemical activities and is widely used in traditional Chinese medicine to treat a variety of diseases and symptoms, especially problems related to qi stagnation and blood stasis. This drug is believed to have the effects of activating blood circulation and removing blood stasis, relaxing muscles and activating collaterals, and is therefore used in traditional Chinese medicine to treat chest and abdominal pain, rheumatic arthralgia, and mass agglomeration. 

It helps promote blood circulation, reduce inflammation and congestion, and relieve pain. In traditional Chinese medicine theory, this drug is often classified as a drug for qi stagnation and blood stasis. This means it helps relieve problems caused by poor Qi and blood flow, such as pain, lumps, congestion, etc. When treating such diseases, tanshinone I is often used in combination with other herbs such as amomum villosum and sandalwood to enhance the efficacy. 

As a natural product molecule, tanshinone I has unique biochemical activity and can be used to treat thoracic and hypochondriac pain, rheumatic arthralgia, mass agglomeration, sores, swelling and pain, falls and other trauma. This compound is often used in conjunction with amomum villosum, sandalwood and other medicines to treat chest and abdominal pain caused by qi stagnation and blood stasis. In addition, this substance also has a certain impact on the production of plant growth hormones.

Why Choose Yuantai Organic?

Demonstrated Track Record:

Since 2014, we've specialized in inquire about, generation, and worldwide showcasing of premium natural fixings. Our mastery in plant extracts guarantees you get items sponsored by profound industry knowledge.

Quality Assurance:

We keep up in-house testing capabilities utilizing HPLC and UV strategies. Each bunch experiences thorough screening for over 400 sorts of pesticide buildups by means of LC-MS/MS, guaranteeing compliance with universal standards.

Vertically Coordinates Supply Chain:

Our organizations with GAP-certified ranches and GMP-certified handling ventures give full prepare control and traceability from soil to shelf.

Customer-Centric Service:

We get it your definition challenges. Our specialized group gives solution-oriented bolster to offer assistance you accomplish ideal comes about.

Certifications

Our facility and products hold multiple internationally recognized certifications:

· Quality & Safety:FSSC 22000, BRC, GMP, ISO 9001, ISO 22000

· Religious & Dietary:Halal and Kosher certified

These certifications ensure you receive ingredients meeting the highest international standards for quality and ethical production.

OEM/ODM Services

We offer flexible customization options to meet your specific requirements:

· Custom purity levels

· Tailored particle size distribution

· Specific packaging configurations

· Private labeling options

· Formula development support

· Stability testing assistance

Our R&D team collaborates with you to develop formulations that match your exact specifications.

Packaging and Delivery

Standard Packaging:

· Inner: Double-layer food-grade polyethylene bags

· Outer: Opaque, light-resistant fiber drums (25kg net weight)

· Special packaging available upon request

Capacity Recommendations:

Store in a cool, dry put (2-8°C favored for long-term capacity), ensured from coordinate UV light and oxygen to anticipate photo-oxidation of the quinone structure.

Delivery:

We work with trusted universal coordinations accomplices to guarantee convenient conveyance. Lead time regularly ranges from 15-30 days depending on arrange volume and destination.

Frequently Asked Questions

Q: How ought to I store this item to anticipate power loss?

A: You must store it in a cool, dry put, ensured from coordinate UV light and oxygen. The quinone structure is vulnerable to photo-oxidation. For long-term capacity, we prescribe 2-8°C in fixed, murky containers.

Q: What's the contrast between Add up to Tanshinones and disconnected Tanshinone IIA?

A: Add up to Tanshinones alludes to the whole of all diterpenoid quinones, giving synergistic impacts. Tanshinone IIA is a particular separated marker compound utilized for high-precision pharmaceutical applications where correct dosing is critical.

Q: Do you offer common beginning verification?

A: Yes, we give C14 radiocarbon testing upon ask to confirm common beginning. Whereas amalgamation is conceivable in research facility settings, our supply is totally from common extraction ofSalvia miltiorrhizafor cost-efficiency and stereochemical keenness.

Contact Us

Ready to source premium-quality botanical extracts for your formulations with Tanshinone powder? Our technical team is here to answer your questions and provide customized solutions.

Email:sales@sxytorganic.com

Tel:86-029-86478251 / 86-029-86119593

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