Bulk Melatonin Powder

Melatonin 99% Powder ：Introduction

Melatonin is a natural compound commonly used in dietary supplements and functional health formulations. It has wide applications in sleep aids, relaxation formulas, and daily health products. YTBIO offers high-purity (99%) Bulk Melatonin Powder, manufactured in strict accordance with quality control standards. Our products boast excellent purity and stable quality, suitable for various dosage forms including capsules, tablets, gummies, powders, and softgels.

Why Choose YTBIO?

Quality Control: Every batch of our products undergoes comprehensive quality inspection to ensure the purity and stability of the finished product.

OEM/ODM Services: We support customized formulations, packaging, labeling, and one-stop finished product manufacturing, covering dosage forms such as powders, tablets, capsules, and gummies.

Global Supply: Our 10,000 square meter factory guarantees our production capacity. 12 years of export experience ensures smooth product development and production.

Document Support: COA, specification sheets, and test reports can be provided upon request.

Minimum Order Quantity: Flexible minimum order quantities; small samples or large orders can be provided upon request.

Test Report

How Melatonin Works?

Sleep is an important guarantee for human health. Humans typically sleep only once a day periodically due to tightly controlled circadian rhythms, in which neurons, neurotransmitters, hormones, and genetic factors regulate sleep propensity, including adenosine, serotonin, and melatonin, among others.

Bulk Melatonin Powder, also known as the sleep hormone, is a core part of the body's sleep-wake cycle. Its production increases with darkness, promotes healthy sleep, and helps adjust the body's circadian rhythm. It acts on MT1, MT2, and MT3 receptors in the body. Among them, MT1 and MT2 receptors are responsible for regulating circadian rhythm and sleep, that is, helping to promote sleep.

Some Health Benefits of Melatonin

1. Good for bone health

A systematic analysis showed that oral melatonin increases osteocalcin. The underlying mechanism may be related to the fact that melatonin affects the formation of osteoblasts and osteoclasts through molecules such as MT2 melatonin receptor, MEK1/2 and MEK5, thereby preventing bone loss. For perimenopausal and postmenopausal women, melatonin may have positive effects on bone health.

2. Good for depression

A systematic analysis showed that oral melatonin can improve depression. If you have depression and your symptoms are worse when you don't get enough sleep, melatonin may help.

3． Improve the success rate of in vitro artificial insemination

Oral administration of melatonin during in vitro fertilization treatment increases the number of mature oocytes and has a tendency, albeit not a significant one, to increase clinical pregnancy rates. For in vitro artificial insemination treatment, melatonin may be helpful, but it is limited by the small sample size and more research is needed to further verify it.

4． Beneficial for weight control

Studies have shown that supplementation with larger doses of melatonin (doses ranging from 3 to 10 mg per day, and intervention times ranging from 3 to 48 weeks) can reduce body weight.

5. Beneficial for children with autism

According to statistics, up to 89% of autistic children have sleep problems, and the presence of sleep disorders may have a negative impact on prognosis. A meta-analysis (including 5 randomized, double-blind, placebo-controlled studies on autism in children) found that the use of melatonin can help improve sleep parameters (including sleep duration and time to fall asleep). Additionally, melatonin appears to improve daytime behavior in people with autism, with few side effects.

6. anti-inflammatory effect

The study found that melatonin supplementation significantly reduced TNF-α (tumor necrosis factor) and IL-6 (interleukin-6) levels, but had little effect on CRP (C-type reactive protein) levels. Melatonin supplementation can help reduce pro-inflammatory mediators.

7． Beneficial for migraines

A comprehensive analysis (including 25 randomized controlled trials with a total of 4499 migraine patients) showed that oral melatonin can help improve the frequency of migraine attacks. Among all the investigated interventions, oral melatonin 3 mg before bedtime is the most ideal pharmaceutical intervention and has the best improvement.

8. Improve primary insomnia

Primary insomnia is simply unexplained insomnia. That is, insomnia that is not caused by disease, mental or environmental causes.

The main symptoms of primary insomnia are difficulty initiating or maintaining sleep, or having non-restorative sleep that lasts for at least 1 month. Melatonin helps reduce the waiting time before falling asleep and increases the total sleep time, improving overall sleep quality.

9. Improve secondary insomnia

In addition to primary factors, insomnia also has secondary factors, usually caused by disease, neurological, environmental, drug or psychiatric causes. Secondary factors are also very common.

Causes of disease include pain, thyroid disease, acid reflux, coronary artery disease, lung disease (chronic obstructive pulmonary disease, asthma, sleep apnea, central alveolar hypoxia syndrome), chronic renal insufficiency, eating disorders, thyroid dysfunction , fibromyalgia, menstrual-related sleep disorders, and pregnancy. Neurological causes include headaches, Parkinson's disease, and more. Environmental factors include excessive noise, harmful odors, bright lights or extreme ambient temperatures, while drug and psychiatric factors include alcoholism, anxiety disorders, mood disorders, panic disorders and other mental illnesses. Exogenous melatonin reduces the time required to fall asleep and increases total sleep time, but has no significant effect on sleep efficiency.

10. Improve fatty liver

High-dose melatonin supplementation (daily doses ranging from 6 to 18 mg, trial periods ranging from 4 to 56 weeks) helps reduce aspartate alaninase (AST), alkaline phosphatase (ALP), and gamma -Glutamyltransferase (GGT).

11． Helpful in adjusting jet lag

Jet lag, also known as circadian rhythm imbalance, is a sleep disorder caused by rapid travel through multiple time zones, causing a mismatch between the body's natural circadian rhythm and the external environment. Oral melatonin (in doses between 500mcg and 5mg) can help prevent or reduce jet lag and appears to be safe when taken occasionally for short periods of time.

12． Improve Alzheimer's disease

Alzheimer's disease is the most common cause of dementia in the elderly. Typical features are progressive decline in memory, language, and intelligence. In addition, sleep and circadian rhythm disorders are common in Alzheimer's disease (especially in the early stages of the disease), and it has been reported that up to 45% of patients may have sleep problems. Studies have shown that melatonin treatment can increase total sleep time at night, but has no significant effect on improving cognitive performance.

Suitable Groups for Melatonin

01elderly

Melatonin is a natural sleeping substance produced by the human body. The reduction of melatonin is the crux of insomnia.

Supplementing melatonin can restore melatonin levels to a youthful state, while repairing the natural pattern of the human body's sleep nerves. It can shorten the time to wake up before bed and the time to fall asleep, regulate rhythm, improve sleep quality, and significantly reduce the number of awakenings during sleep. The light sleep stage is short and the deep sleep stage is prolonged.

02People with poor sleep quality

Melatonin can shorten the time to wake up before bed and the time to fall asleep, significantly reduce the number of awakenings during sleep, shorten the light sleep stage, and extend the deep sleep stage, thereby improving sleep quality.

03 People suffering from jet lag and working shifts

The secretion of melatonin in the human body has a circadian rhythm, with more melatonin being secreted at night.

Melatonin can reset the body's biological clock, adjust jet lag, correct jet lag, help reverse jet lag, and improve the sleep of shift workers.

Potential Functional Applications

Sleep Support Products: Widely used in nighttime and sleep support products.

Relaxation Products: Commonly used for relaxation and balancing daily life.

Functional Products: Suitable for modern nutritional supplements targeting health-conscious consumers.

The above statements have not been evaluated by the U.S. Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.

Recommended melatonin product formula combinations:

·Melatonin + Magnesium

·Melatonin + L-Theanine

·Melatonin + GABA

·Melatonin + Ashwagandha

·Melatonin + Vitamin B6, etc.

You can choose from our existing design products：

Contact Us

From Bulk Melatonin Powder raw ingredients to finished formulations, YTBIO supports your global supplement business with stable quality and professional service.

Tel:86-029-86478251 / 86-029-86119593
Whatsapp:8617782577059
Email:sales@sxytorganic.com